Market Signal Briefing

Cash position of CHF 2.3 million at end of H1 2025 GABAB PAM chronic cough candidate demonstrated robust anti-tussive activity in disease models Regained rights to phase 2 mGlu2 PAM asset, ADX71149 Indivior advanced GABAB PAM substance use disorders program successfully through IND enabling studies Entered option agreement with Sinntaxis for exclusive license to intellectual property covering the use of mGlu5 NAM in brain injury recovery Invested in Stalicla SA, confirming commitment to advancing innovative treatments for CNS disorders Ad Hoc Announcement Pursuant to Art. 53 LR Geneva, Switzerland, September 30, 2025 - Addex Therapeutics (SIX and Nasdaq: ADXN), a clinical-stage biopharmaceutical company focused on developing a portfolio of novel small molecule allosteric modulators for neurological disorders, today reported its half-year and second quarter financial results for the periods ended June 30, 2025, and provided a corporate update.

Recently granted CE Mark, the novel test delivers improved sensitivity and accuracy for faster and more reliable diagnosis in emergencies.The test helps clinicians quickly identify heart attack and rule out non-cardiac causes, ensuring patients receive the care they need at the earliest opportunity.The global TSIX clinical study involved more than 13,000 participants, validating performance across a diverse population that reflects real-world healthcare settings.1,2 Basel, 30 September 2025 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced the primary results from the TSIX Study Program, which evaluated the performance of its new sixth-generation high-sensitivity Troponin T test for diagnosing heart attacks. Presented at the European Society for Emergency Medicine (EUSEM) 20252 and the European Society of Cardiology (ESC) 20251, the study results showed that the Elecsys® Troponin T hs Gen 6 test was able to identify acute myocardial infarction (AMI), or heart attack, and identify those not having an AMI, with a high level of precision.2,3 This supports the efficient triage of patients arriving at the emergency department, ensuring healthcare resources can be focused where they are needed most. This data announcement follows the recent CE Mark approval for the test.

As one of the top three reasons for emergency care visits,4 chest pain creates significant anxiety and uncertainty for patients whilst putting pressure on healthcare services. Yet only one in every ten patients who presents with symptoms will actually be experiencing a heart attack.5 With 49% of emergency departments in Europe reporting overcrowding on a frequent basis,6 the ability to quickly and reliably identify those patients who are suffering from AMI, and to rule out those who are not, is crucial in ensuring the best possible outcomes for patients.

"Coronary artery disease continues to place an immense strain on global health systems, particularly in emergency care, where cases of chest pain are among the most challenging presentations to evaluate,” said Matt Sause, CEO of Roche Diagnostics. “Our new test enables clinicians to detect even the smallest elevations in troponin levels – a critical biomarker for heart attack – with high confidence. This ensures that in a situation when every second counts, patients receive the life-saving care they need at the earliest opportunity, and emergency services can prioritise resources to deliver care effectively to those in urgent need."

About Roche Diagnostics’ commitment to heart health
With a 30-year legacy in troponin innovation, Roche was the first company in the world to introduce high-sensitivity troponin tests. And Roche's troponin test was the first to receive FDA approval. Building on this legacy, the novel test is the first in a series of anticipated approvals for Roche, reflecting the company's vision for the future of coronary artery disease (CAD) management. This includes a portfolio of innovative tests that enable consistent and precise biomarker measurements to be reliably compared across healthcare settings. It also includes future acute coronary syndrome (ACS) offerings that will combine next-generation digital algorithms, biomarkers, near-patient care devices, and laboratory analysers.

About the TSIX Study Program
Forming the basis for regulatory approval, the comprehensive TSIX study program recruited a total of over 13,000 individuals.1,4 It is the first global clinical study program of its kind to be performed in the use of troponin testing, involving patients in the US, China, Japan and the EU, and reflects Roche’s ambition to work towards more standardised care across the world.

The REF-TSIX study was designed to establish the standard upper reference limits (URLs) for troponin levels in the blood.1 These limits represent the highest expected concentration of troponin in a healthy population, providing the benchmarks used to diagnose myocardial infraction. The study prospectively collected plasma and serum samples from a diverse global population to ensure the assay's accuracy across different demographics and healthcare settings. Data presented at European Society of Cardiology congress 2025 showed a 99th percentile URLs of 27 ng/L for the overall population and sex-specific URLs of 18 ng/L for females and 32 ng/L for males.1 These findings confirm the test's consistency and accuracy, meeting the highest benchmarks for clinical diagnostics as recommended by the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC).7

To validate the clinical performance of the newly established URLs, the prospective, international, multicenter, longitudinal cohort study PERFORM-TSIX enrolled 5,631 patients across 50 sites,2,4 presenting to emergency departments with symptoms of ACS. Up to five samples were collected at intervals after presentation at the emergency department, to provide a detailed assessment of the test's performance across time points.4

The study data demonstrated that the assay was highly effective at detecting heart attacks, meeting its primary endpoint using the universal 99th percentile URL at three hours post emergency department presentation.3 Moreover, the study data showed that 56.6% of patients were able to be discharged in the first hours after presentation with a negative predictive value of 99.7%, underlining its excellent clinical performance.2,4

About Roche
Founded in 1896 in Basel, Switzerland, as one of the first industrial manufacturers of branded medicines, Roche has grown into the world’s largest biotechnology company and the global leader in in-vitro diagnostics. The company pursues scientific excellence to discover and develop medicines and diagnostics for improving and saving the lives of people around the world. We are a pioneer in personalised healthcare and want to further transform how healthcare is delivered to have an even greater impact. To provide the best care for each person we partner with many stakeholders and combine our strengths in Diagnostics and Pharma with data insights from the clinical practice.

For over 125 years, sustainability has been an integral part of Roche’s business. As a science-driven company, our greatest contribution to society is developing innovative medicines and diagnostics that help people live healthier lives. Roche is committed to the Science Based Targets initiative and the Sustainable Markets Initiative to achieve net zero by 2045.

Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan.

For more information, please visit www.roche.com.

All trademarks used or mentioned in this release are protected by law.

References
[1] Daniels LB et al. Establishing reference values in healthy participants for a next generation cardiac troponin T high-sensitivity assay – the REF-TSIX global reference study. Presented at European Society of Cardiology Congress. 2025 August
[2] Peacock WF et al. Primary results of PERFORM-TSIX, a prospective, international, observational, longitudinal cohort study evaluating clinical performance of the next generation cardiac troponin T high-sensitivity Gen 6 assay in acute coronary syndrome myocardial infarction. Presented at European Society of Emergency Medicine September 2025
[3] F. Hoffmann-La Roche Ltd. Elecsys® Troponin T hs Gen 6 Method Sheet. (v.2.0). 2025
[4] Audrey J. Weiss, Ph.D., and H. Joanna Jiang, Ph.D., Agency for Healthcare Research and Quality, Most Frequent Reasons for Emergency Department Visits, 2018. Available at: https://hcup-us.ahrq.gov/reports/statbriefs/sb286-ED-Frequent-Conditions-2018.jsp
[5] Fanaroff AC, Rymer JA, Goldstein SA, Simel DL, Newby LK. Does This Patient With Chest Pain Have Acute Coronary Syndrome?: The Rational Clinical Examination Systematic Review. JAMA. 2015 Nov 10;314(18):1955-65. doi: 10.1001/jama.2015.12735. PMID: 26547467.
[6] Velt KB, Cnossen M, Rood PPM, Steyerberg EW, Polinder S, Lingsma HF; CENTER-TBI investigators. Emergency department overcrowding: a survey among European neurotrauma centres. Emerg Med J. 2018 Jul;35(7):447-448. doi: 10.1136/emermed-2017-206796. Epub 2018 Mar 21. PMID: 29563151.
[7] Aakre, K. M., Saenger, A. K., Body, R., Collinson, P., Hammarsten, O., Jaffe, A. S., ... & Apple, F. S. (2022). Analytical considerations in deriving 99th percentile upper reference limits for high-sensitivity cardiac troponin assays: educational recommendations from the IFCC committee on clinical application of cardiac bio-markers. Clinical chemistry, 68(8), 1022-1030.

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Media Investor Release Troponin T Test English

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The Bitcoin community is no stranger to heated debates, but the latest controversy around a rumored Bitcoin Redaction Fork has reignited one of the oldest philosophical battles in crypto: should Bitcoin remain an untouchable, immutable ledger, or should it adapt to external pressures to remove illicit or arbitrary data

Institutional confidence in Solana (SOL) remains strong, making it one of the stable altcoins in the market. Treasury wallets now hold over 20.9 million SOL, roughly 3.64% of the total supply, indicating that large investors are increasingly viewing SOL alongside Bitcoin and Ethereum as part of diversified crypto portfolios.

Companies like Forward Industries and Brera Holdings have disclosed their asset exposure, while ARK has added Solana-related equities and continues to emphasize the network’s expansion.

Meanwhile, speculation about a potential Solana staking ETF has gained momentum; if approved, it could reduce circulating supply and provide yield access, potentially attracting significant new capital into SOL. Mid-cycle analyst targets of $300–$500 reflect this institutional interest along with rising on-chain activity.

SOL's price trends to the upside but with some losses on the daily chart. Source: SOLUSD chart on Tradingview
Firedancer + Alpenglow: Leap in Performance vs. Decentralization Risk
Solana’s technology roadmap provides another boost. Jump Crypto’s Firedancer client proposes SIMD-0370 to remove the fixed compute block limit, allowing higher-performance validators to process more complex blocks and increasing overall throughput.

At the same time, the Alpenglow upgrade (testnet scheduled for December) aims to drastically reduce transaction finality, from approximately 12.8 seconds to 150 milliseconds, making Solana the fastest major chain. These changes could strengthen Solana’s leadership in high-volume DeFi and payments.

However, critics warn that increasing centralization may occur if smaller validators cannot afford the necessary hardware upgrades. The primary challenge is striking a balance between raw speed and validator diversity, which is crucial for evaluating the network’s long-term resilience.

Price Levels: Can Solana (SOL) Bulls Defend $207?
Currently, SOL hovers near $208–$210, up modestly on the day as momentum rebuilds. The market now focuses on $207 as the first support level; a sustained hold preserves the uptrend and keeps a retest of $230–$253 possible, with $257 (the 52-week high) remaining above.

Losing $207 opens the door to $190–$185 as the next demand zone, and a deeper shakeout could test $165–$167. Short-term sentiment is supported by improving tape dynamics, higher spot volumes, and active addresses, although macro factors remain a swing factor.

For traders, the constructive setup is to hold $207, reclaim $223–$230, and then challenge $253–$257. For investors, the thesis relies on three pillars: increasing treasury ownership and potential ETF catalysts, throughput leadership from Firedancer and Alpenglow, and expanding real-world utility across DeFi and commerce.

If Solana maintains support while upgrades happen as scheduled, the path toward new highs strengthens; if not, expect a choppy Q4 with value emerging around the $185 area.

Cover image from ChatGPT, SOLUSD chart from Tradingview

Solana whale sells $31.59M in $SOL, yet charts hint at bullish continuation with eyes on $250 resistance.

Izabela Anna2 min read

30 September 2025, 01:10 AM

Image: ShutterstockSolana ($SOL) has experienced a dynamic trading session as whales aggressively adjust their positions. Today, a single whale reportedly sold $31.59 million in $SOL, highlighting significant profit-taking on minor price pumps, according to analyst TedPillows. Despite this selling pressure, the market shows potential for continued upside if key technical levels hold.

Weekly Chart Hints at Bullish ContinuationAccording to CryptoJelleNL, Solana’s weekly chart shows a prominent cup-and-handle pattern forming above $180 support. The recent bounce near $206 confirms a successful retest of the breakout zone. The $250 mark remains the last hurdle for buyers, and clearing this resistance could trigger a sustained rally toward $300–$340 by year-end. 

Source: X

Conversely, a failure to overcome $250 may result in a brief pullback toward $190–$200 before another attempt. Consequently, the current setup signals bullish continuation if buyers can defend the retest and push decisively through this key resistance.

Daily Chart Insights and Liquidity SweepsOn the daily timeframe, Solana has reclaimed the 50-day simple moving average (SMA) after a brief dip, signaling renewed bullish interest, according to Umair Crypto. The recent sweep below the SMA likely gathered liquidity, setting up a potential move toward resistance around $229–$232. 

Source: X

Nevertheless, traders remain cautious, as weekend closes often spark debates about the validity of short-term movements. A confirmed close above $210 would strengthen the bullish outlook, while slipping back under the SMA could target support levels at $185 and $161.

The RSI has recovered from oversold conditions but remains mid-range, suggesting measured buying interest. With the current price around $214, $SOL has gained 3.56% in the past 24 hours, despite a 1.24% decline over the last week. Trading volumes remain robust, with $7.31 billion exchanged in the last 24 hours, reflecting active investor engagement.

Regulatory Updates Add Another LayerBeyond technical factors, regulatory news continues to influence sentiment. Journalist Eleanor Terrett reports that the SEC has asked issuers of $SOL, $LTC, $XRP, $ADA, and $DOGE ETFs to withdraw their 19b-4 filings following the approval of generic listing standards. Withdrawals could begin this week, removing some previous regulatory hurdles for crypto ETFs.

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Izabela Anna

Izabela Anna is a knowledgeable freelance journalist, who boasts over five years of experience covering the cryptocurrency market. Her tenure has seen her navigate through the ebbs and flows of multiple market cycles, giving her a deep understanding within. Her journalistic focus lies in dissecting price action dynamics, scrutinizing the on-chain landscape, and providing insights from a technical perspective, making her a trusted voice in the realm of cryptocurrency reporting.

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Latest Solana (SOL) News Today

The cryptocurrency market staged a weekend rebound, with Solana (SOL), Dogecoin (DOGE), Cardano (ADA), Ethereum (ETH), and XRP among the top performers. Prices rose between 3% and 4% over the past 24 hours as short liquidations intensified, offering traders fresh optimism after a difficult week.

Bitcoin traded listlessly as September wraps up, caught inside a tight price band and showing signs of weakening momentum.

Based on reports using CryptoQuant data and commentary by Axel Adler, demand cooled after the market failed to hold above $115,000, leaving traders watching a narrow corridor for the next move. The mood is neither euphoric nor panicked — it is cautious.

Mounting Pressure At Descending Highs
Over the past week Bitcoin swung between a local high near $115,550 and a low around $108,400. For the last sessions it settled into an even tighter $108,750–109,740 band. Sellers stepped in at lower highs, keeping the price from climbing back to the prior range.

According to Adler, those descending highs are a warning sign because they show buyers are losing early ground. Immediate resistance sits around $111,000–112,000, based on on-chain flows and exchange behavior.

Move past that and bulls could try to retake $114,000–115,400. Fail to defend $108,750 and the path down may quicken toward $106,000–105,000.

Momentum Has Turned Cautious
CryptoQuant’s 30-day momentum index finished the week near -2%, down from +1% at the start, a swing of three percentage points. Momentum readings this period ranged from -6% to +1%, and only two of seven sessions closed above zero.

Those figures underline how the loss of the $114,000–115,000 support coincided with falling buying pressure. Traders often look for sustained positive momentum to confirm a rally. According to Adler, a clear recovery would need a return above $112K and several days of positive momentum to shift the tone back toward an uptrend.

BTCUSD trading at $112,173 on the 24-hour chart: TradingView
Market Structure And What It Means
The current pattern is a classic consolidation after a failed breakout. Buyers tried and failed to keep prices north of $115,000, and that shortfall left the market in a neutral-to-bearish stance.

Reports have disclosed that the week’s range and the momentum slide make an immediate strong advance unlikely without fresh demand. At the same time, there is no sign of a full-scale sell-off. Liquidity remains present near established supports.

Key Levels To Watch
A decisive push above the $111,000–112,000 resistance band could prompt a test of $114,000–115,400. The $108,600 base remains a key level. A break below it without a swift rebound could open the way toward stronger support between $106,000 and $105,000.

Shifts in on-chain demand and exchange flows are expected to provide clearer signals, as price action alone may appear steady while underlying activity changes.

Featured image from Gemini, chart from TradingView

A long-dormant Bitcoin wallet containing approximately 400 BTC—worth $44 million at today's prices—moved funds for the first time in 12 years on Sunday, according to data from blockchain analytics platforms Lookonchain and Arkham Intelligence.

Trusted Editorial content, reviewed by leading industry experts and seasoned editors. Ad Disclosure

Bitcoin and Ethereum ETFs experienced their worst weekly stretch since debut, as risk appetite declined and investors de-risked heading into quarter-end.

U.S. spot Bitcoin ETFs saw approximately $902.5 million in net outflows for the week of Sept. 22–26, ending a four-week inflow streak. Ethereum ETFs lost about $795.6 million, marking their largest weekly redemptions since launch.

The outflows were uneven: Fidelity’s FBTC led BTC outflows, while BlackRock’s IBIT and Invesco’s BTCO defied the trend with $173.8 million and $10 million of inflows, respectively. On the ETH side, several issuers experienced large single-day withdrawals, showing how quickly flows can reverse when macro risk increases.

Macro Headwinds Keep Buyers Cautious
The reversal came as traders weighed new U.S. tariff announcements and lingering uncertainty about the Fed’s rate cuts ahead of key inflation data. Those headlines revived fears of a growth and liquidity squeeze, driving a quick reset across risk assets.

Bitcoin briefly slipped below pivotal support intraday before rebounding, while Ethereum mirrored the move with a shallow bounce. Despite the week’s pain, September still shows net inflows for Bitcoin ETFs ($2.57B), a notable improvement from August’s outflows, evidence that institutional adoption remains intact.

For now, the market’s message is clear: without a more dovish macro backdrop or cleaner inflation prints, allocators may remain selective, trimming core BTC/ETH exposure when it is strong and adding only on clear confirmations.

BTC's price trends to the upside on low timeframes. Source: BTCUSD on Tradingview
Alternative Crypto ETFs Take Spotlight Over Bitcoin and Ethereum
Beneath the headline of redemptions, some desks report rotations toward thematic or alternative crypto ETFs (e.g., Solana, XRP) as allocators seek uncorrelated catalysts.

That discussion overlaps with speculation about a potential BlackRock XRP spot ETF, with market models suggesting $4–$8B of first-year inflows if such a product were filed and approved. Although no filing has been confirmed, XRP’s quick settlement times and low fees keep it on institutions’ radar.

Nevertheless, the week’s outflows serve as a reminder: macro factors outweigh micro in the short term. As October progresses, focus on whether BTC funds resume steady inflows, if ETH redemptions decrease, and how upcoming inflation data influences Fed expectations.

Until these factors align positively, volatility will remain high, and ETF flow reports will continue to be the best real-time indicators of institutional confidence.

Cover image from ChatGPT, BTCUSD chart from Tradingview

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Ethereum price started a recovery wave above $4,150. ETH is now consolidating and might aim for more gains if it clears the $4,220 resistance.

Ethereum remained stable above $4,020 and started a recovery wave.
The price is trading above $4,150 and the 100-hourly Simple Moving Average.
There is a connecting bullish trend line forming with support at $4,100 on the hourly chart of ETH/USD (data feed via Kraken).
The pair could continue to move up if it settles above $4,220 and $4,250.

Ethereum Price Eyes More Gains
Ethereum price remained supported above the $4,020 level and started a recovery wave, like Bitcoin. ETH price was able to recover above the $4,050 and $4,120 resistance levels.

There was a clear move above the 61.8% Fib retracement level of the downward wave from the $4,275 swing high to the $3,826 low. The bulls even pushed the price above $4,200. Besides, there is a connecting bullish trend line forming with support at $4,100 on the hourly chart of ETH/USD.

Ethereum price is now trading above $4,150 and the 100-hourly Simple Moving Average. It is also above the 76.4% Fib retracement level of the downward wave from the $4,275 swing high to the $3,826 low.

Source: ETHUSD on TradingView.com
On the upside, the price could face resistance near the $4,220 level. The next key resistance is near the $4,250 level. The first major resistance is near the $4,275 level. A clear move above the $4,275 resistance might send the price toward the $4,320 resistance. An upside break above the $4,320 region might call for more gains in the coming sessions. In the stated case, Ether could rise toward the $4,450 resistance zone or even $4,500 in the near term.

Pullback In ETH?
If Ethereum fails to clear the $4,250 resistance, it could start a fresh decline. Initial support on the downside is near the $4,150 level. The first major support sits near the $4,100 zone and the trend line.

A clear move below the $4,100 support might push the price toward the $4,050 support. Any more losses might send the price toward the $4,000 region in the near term. The next key support sits at $3,880.

Technical Indicators

Hourly MACD – The MACD for ETH/USD is gaining momentum in the bullish zone.

Hourly RSI – The RSI for ETH/USD is now above the 50 zone.

Major Support Level – $4,100

Major Resistance Level – $4,250

Joerg Hiller
Sep 30, 2025 04:13

Sui's presence at Korea Blockchain Week 2025 highlighted its growing influence in the digital asset space, featuring key discussions on AI, gaming, and blockchain advancements.

The Korea Blockchain Week (KBW) 2025 served as a significant platform for Sui, bringing together its leadership, partners, and community to spotlight its growing influence within the digital asset realm. According to Sui Foundation, the week-long series of events underscored Sui's institutional relevance and cultural impact in the Asia-Pacific region.

EastPoint: Setting the Stage
The event kicked off with EastPoint:Seoul, a private conference where key figures, including Kevin Boon, President of Mysten Labs, discussed the future of digital assets in Korea. Boon's insights into U.S. regulatory developments provided a global perspective to local stakeholders eager to understand the implications for Korean markets.

Impact and Innovation at KBW
During the KBW: IMPACT conference, Sui showcased its thought leadership and community engagement. Notable sessions included presentations by Adeniyi Abiodun and Kostas Chalkias, both Co-Founders of Mysten Labs. Abiodun introduced the Sui Stack as a coordination layer for applications and AI, while Chalkias explored blockchain's intersection with AI, highlighting new frontiers in digital technology.

Community Engagement and Gaming Focus
Midweek events focused on community-building and gaming, with over 800 partners and builders attending an elegant evening gathering in Seongsu. Industry leaders discussed the flexibility of Sui's architecture in game design and deployment. The day concluded with an interactive gaming event, "Ready. Sui. Play!" in Gangnam, engaging developers and players in hands-on experiences.

Sui Builder House: APAC
The week culminated with the Sui Builder House: APAC event, drawing 600 participants eager to explore regional strategies and product innovations. The program featured significant announcements, including new product milestones like Slush and BTCfi integrations, and showcased how partners in payments, gaming, and AI are leveraging the Sui Stack to transform their industries.

Future Prospects
The events of "Sui in Seoul" demonstrated the convergence of regulation, technology, and culture as Sui continues to strengthen its presence in the APAC region. With the success of KBW 2025, Sui is poised for further growth and innovation, with upcoming events like SuiFest in Singapore promising to build on this momentum.

Image source: Shutterstock

sui
blockchain
korea blockchain week
innovation

AlphaTON Capital has secured $71 million to strengthen its role in the Telegram ecosystem. The Nasdaq-listed firm confirmed the financing included a $36.2 million private placement and a $35 million loan facility with BitGo Prime.

Bitcoin price has rebounded from September lows as rising volumes, institutional inflows, and supportive technicals fuel expectations of a Q4 rally.

Summary

Bitcoin price rebounded to $114,603, up 2.5% in 24 hours, supported by rising trading volume and institutional inflows.
Analysts say late-September gains mark the start of a potential Q4 rally, with some forecasting new highs near $180K.
On-chain data shows accumulation by long-term holders, reduced exchange reserves, and improving technical signals.

After a volatile September, Bitcoin has gained momentum as it enters the last quarter of 2025, rising back above $114,000. Bitcoin was up 2.5% in the last day, trading at $114,603 at the time of writing. The most popular cryptocurrency is currently only 7.7% below its peak of $124,128 on Aug. 14.

Additionally, market activity has significantly increased. Following weeks of muted sentiment, the daily trading volume for Bitcoin (BTC) increased by 70% to $58.8 billion in the last 24 hours, indicating a resurgence of investor activity.

Bitcoin expected to rally into Q4
In a recent analysis, CryptoQuant contributor XWIN Research Japan explained that Bitcoin’s sharp rebound in late September was no coincidence. The Federal Reserve’s Sept. 17 interest rate cut weakened the U.S. dollar and lifted gold to new highs, setting the stage for Bitcoin to benefit as a digital alternative.

As per XWIN’s observation, capital often flows into gold first before rotating into Bitcoin as risk appetite improves, and the same pattern played out last month.

Institutional demand added fuel. The Securities and Exchange Commission’s relaxation of Exchange Traded Fund listing rules boosted confidence, leading to new XRP (XRP) and DOGE (DOGE) products and steady inflows into major funds like BlackRock’s IBIT and Fidelity’s FBTC.

XWIN concluded that these shifts, combined with reduced selling from both short- and long-term holders, show that the September rally was not a random bounce but the beginning of a stronger phase heading into Q4.

Bitcoin accumulation points to higher targets
Another CryptoQuant contributor, Carmelo Alemán, highlighted broader on-chain signals that reinforce the bullish case. Over the course of the last year, Bitcoin’s market capitalization has increased from $870 billion to $1.07 trillion, driven by average daily inflows of $385 million. Global liquidity is still growing, and large wallets and miners are gradually building up.

According to Alemán, these factors suggest that Bitcoin is currently in an accumulation phase prior to a subsequent leg up, with Q4 probably bringing new all-time highs. He went further, predicting that if institutional inflows and liquidity trends hold, Bitcoin could hit $180,000 before the year is out.

Bitcoin price technical analysis
These views are also supported by the charts. The most recent recovery was triggered by oversold relative strength index levels in September, and Bitcoin has maintained strong support between $108,000 and $110,000.

Bitcoin daily chart. Credit: crypto.news
Moving averages across all major timeframes are now flashing buy signals, suggesting the broader trend is tilted upward. Resistance remains at the $118,000 level, followed by the August all-time high around $124,000.

If these barriers are cleared, analysts argue that a rally toward $150,000 to $180,000 by year-end is plausible, provided liquidity inflows and institutional interest continue.

The Bitcoin price opened Monday with a slight recovery, reclaiming the $113,000 mark after a dip that brought the price down to $109,000—a level that has proven to be significant support for the top cryptocurrency. Despite this temporary bounce, one expert warns of further challenges ahead for bullish investors.

Warns Of Further Bitcoin Price Drops 
In a recent post on social media platform X (formerly Twitter), Doctor Profit expressed confidence in his market analysis, indicating that BTC is on track to reach his projected target range between $90,000 to $94,000, meaning an additional 20% drop for the Bitcoin price. 

He posited that the cryptocurrency is poised to move toward a new short-term downside target at approximately $106,000. According to his assessment, a minor bounce in this area could attract additional liquidity before the market potentially moves lower.

BTC’s next price target below $100,000. Source: Doctor Profit on X
Doctor Profit also paints a bleak picture of the broader economic landscape, highlighting troubling signs such as Japan’s 10-Year Bond Yield reaching its highest level since the Global Financial Crisis. 

He notes that the repo-to-reserves ratio is approaching 99%, a metric that hints at funding stress and margin strain, leading to forced selling. While he acknowledges that a surge in liquidity from central banks could provide a bullish pivot, he remains skeptical given the current market conditions.

The analyst also referenced a range of indicators and charts he has shared since August, emphasizing that many key market charts, including the Dow Jones, are at significant resistance levels, some of which have formed over a century. 

He pointed out the record levels of alleged insider selling witnessed in recent weeks, alongside a surge in retail investor inflows, suggesting a disconnect between retail enthusiasm and the actions of larger players in the market.

October Could Signal Recovery 
In contrast to Doctor Profit’s cautious stance, market expert Timothy Peterson offers a more optimistic outlook for the Bitcoin price trajectory in the months to come. Peterson believes that October could bring a positive shift for Bitcoin, drawing on historical trends and current market dynamics. 

As recently reported by NewsBTC, Peterson has outlined two potential bullish scenarios that he believes remain for the cryptocurrency: one forecasting a rise to as high as $240,000, while another more conservative estimate suggests a surge to $160,000.

As the month of September draws to a close, Doctor Profit’s prediction that Bitcoin would trade below $100,000 could still play out. With only a 9% decline needed to breach the $100,000 threshold, the outlook remains uncertain.

The daily chart shows BTC’s price recovery above $113,000. Source: BTCUSDT on TradingView.com
Featured image from DALL-E, chart from TradingView.com 

ConocoPhillips is integrating new assets as it focuses on its best properties, setting up for stronger returns when oil prices rise again.

If there is one thing that investors need to understand about the energy sector, it is that oil and natural gas prices are inherently volatile. But there's a somewhat counterintuitive takeaway here. Sometimes the best investment opportunities arise when business in the oil space isn't going so well.

Which is why investors might want to buy ConocoPhillips (COP -2.67%) today. Indeed, the company's successful business overhaul is so obvious that it is hard not to notice (at least partly because the company is so happy to point it out).

Image source: Getty Images.

Not such a great quarter for sales and earnings
ConcoPhillips' earnings in the second quarter of 2025 weren't great when you compare it to the same quarter in 2024, with a drop from $1.98 per share last year down to just $1.56 this year. But that doesn't even do justice to the energy company's earnings decline, since pulling out a one-time gain in the second quarter of 2025 drops the total down to $1.42 per share. That's the worst quarterly earnings outcome in over a year and down sequentially from even the first quarter.

But that's kind of how things go in the energy sector, where oil and natural gas prices drive the top and bottom lines of the income statement. In fact, it isn't even remotely unusual for ConocoPhillips' earnings to be volatile from quarter to quarter. That said, the energy sector is, generally, not in the best place today relative to the highs achieved in the price rebound coming out of the coronavirus pandemic.

For example, ConocoPhillips' share price has fallen around 25% from its late 2022 highs. For comparison, Brent Crude, a key international oil benchmark, and West Texas Intermediate Crude, a key U.S. oil benchmark, have both lost about a third of their value over the same span. This could actually be a good time for more aggressive investors to consider buying ConocoPhillips.

An obvious reason to like ConocoPhillips
Assuming you can stomach the uncertainty of a commodity-based business like ConocoPhillips, there are good things happening at the company. Notably, it has been integrating the acquisition of Marathon Oil and executing above expectations. For example, it added 25% more resources than projected when the deal was inked. Despite that, it also managed to reduce the number of rigs it was operating on the added properties by 30%. All in, it was able to double the business synergies it projected, saving $1 billion in costs annually. And management managed to set up $2.5 billion in dispositions in nine months, when it had previously been looking to shed $2 billion in assets over a two-year period.

The dispositions are a special consideration. ConocoPhillips isn't looking to get big for the sake of getting big. It is attempting to optimize its portfolio of assets so it can focus on only its best properties. That, in turn, should help to improve profitability over the long term. To be fair, even the best properties won't change the variability in energy prices. But wider profit margins means the company will make more money when times are good and have more downside leeway when times are bad. ConocoPhillips isn't hiding its success, it is proudly telling investors all about what it has achieved. In other words, there are obvious improvements taking shape at the business.

This is the setup for better performance in the future
To state the obvious again, as an energy company, energy prices are going to dictate ConocoPhillips' financial results. Conservative investors looking for consistent earnings or reliable dividends (the company pays a dividend regularly, but the amount of the dividend is highly variable) probably shouldn't buy the stock.

But if you are looking for direct exposure to energy prices, ConocoPhillips could be a solid choice given management's efforts to overhaul the business. When commodity prices take off again, the upgrades made to the portfolio will help supercharge ConocoPhillips' financial results. And Wall Street will almost certainly reward the stock for that.

Reuben Gregg Brewer has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.

Analyst’s Disclosure:I/we have a beneficial long position in the shares of AGNC, NLY either through stock ownership, options, or other derivatives. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

Seeking Alpha's Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

Analyst’s Disclosure:I/we have no stock, option or similar derivative position in any of the companies mentioned, but may initiate a beneficial Long position through a purchase of the stock, or the purchase of call options or similar derivatives in BLBD over the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

Seeking Alpha's Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

IDT Corporation (NYSE:IDT) Q4 2025 Earnings Call September 29, 2025 5:30 PM EDT

Company Participants

Bill Ulrey - Vice President of Investor Relations & External Affairs
Samuel Jonas - Chief Executive Officer
Marcelo Fischer - Chief Financial Officer

Conference Call Participants

William Vaughan

Presentation

Operator

Good evening. Welcome to the IDT Corporation's Fourth Quarter and Full Fiscal Year 2025 Earnings Conference Call. [Operator Instructions] Please note, this conference call is being recorded. I will now turn the call over to Bill Ulrey of IDT Investor Relations. Bill, you may begin.

Bill Ulrey
Vice President of Investor Relations & External Affairs

Thank you, John. In today's presentation, IDT's Chief Executive Officer, Shmuel Jonas; and Chief Financial Officer, Marcelo Fischer, will discuss IDT's financial and operational results for the 3- and 12-month periods ended July 31, 2025. After their remarks, they will be happy to take your questions. Any forward-looking statements made during this conference call, either in their remarks or during the Q&A that follows, whether general or specific in nature, are subject to risks and uncertainties that may cause actual results to differ materially from those which the company anticipates. These risks and uncertainties include, but are not limited to, specific risks and uncertainties discussed in the reports that IDT files periodically with the SEC.

IDT assumes no obligation either to update any forward-looking statements that they have made or may make or to update the factors that may cause actual results to differ materially from those that they forecast. In their presentation or in the Q&A session, IDT's management may make reference to non-GAAP measures, including adjusted EBITDA, non-GAAP net income, non-GAAP earnings per share, NRS's Rule of 40 score and adjusted net cash provided by operating activities. Schedules provided in the IDT earnings release reconcile these non-GAAP measures to their nearest corresponding GAAP measures. Please note

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Toronto, Ontario – TheNewswire - September 29, 2025 – Hybrid Power Solutions Inc. (CSE: HPSS) (OTC: HPSIF) (FSE: E092) ("Hybrid" or the "Company"), an emerging leader in the delivery of fuel-free clean power solutions, announces its financial results for the fiscal year ending May 31, 2025. The Annual Financial Statements, Management Discussion and Analysis and financial certifications have been filed on SEDAR+ and can be viewed on the Company’s investor website at https://investhps.com/.

Fiscal Year 2024 Business Highlights

Signed strategic partnerships with multiple domestic and US based distributors including Colony Hardware, Drive Products, Tom Miller & Associates, TEC Sales and Civic Grid.  

Sale of 105 Batt Pack Pros (BPP) to California based major utility entity. 

Sale of BPP’s to US based military divisions including US Marines, US Air Force & California Air National Guard. 

Ongoing demo with major Canadian rental company.  

Ongoing demo for National Home Builder in Canada. 

Spark and solar package sale and ongoing pilot program with leading US based construction firm. 

Secured listing with California Air Resource Board. 

Signed Letter of Intent with Green Maple Energy Solutions Limited for the import of energy solutions into Nigeria and across the African continent.  

Additional 18 pilot and demo units currently undergoing testing with construction, mining, utilities, home builders and distributors. 

Launched new Hybrid Spark sizes to accommodate increasing power demands.  

Initiated development of cross-platform fleet management and remote monitoring software to integrate artificial intelligence functionality, GPS tracking, remote diagnostics and both Wi-Fi and cellular communication options.   

Fiscal Year 2024 Financial Highlights

Revenue for period ending May 31, 2025 of $2,801,100 versus revenue of $2,437,507 for the period ending May 31, 2024, an increase of 15%. 

Expenses for the period ending May 31, 2025 of $3,254,599 versus expenses of $6,506,186 for the period ending May 31, 2024, a decrease of 50%. 

Net loss for the period ending May 31, 2025 of $2,928,841 versus a net loss of $6,512,440 for the fiscal year ending May 31, 2024. 

Fiscal Year 2024 Corporate Highlights

Appointment of Muneer Yoosuf, CGMA to the position of Chief Financial Officer. 

Appointment of Mr. Bruno Antidormi, P. Eng., G.S.C. to the board of directors. 

Appointment of Mr. Alvin Kersting to the board of directors. 

Secured matching funding from Federal Economic Development Agency for Southern Ontario for C $2,250,000. 

Completed non-brokered shelf offering of C $541,800. 

Completed non-brokered prospectus offering of C $600,000. 

CEO and Founder Francois Byrne states: “Over the past year, we have taken bold steps to ensure Hybrid is built on a stronger foundation – streamlining operations, reshaping our engineering team, and investing in Canadian innovation. As we approach our 10-year anniversary, our pipeline of opportunities has never been stronger, with opportunities that reflect the confidence major industries and partners have in our solutions. We have learned from our challenges and are well positioned to deliver sustainable, long-term value for our customers, partners, and shareholders.”

About Hybrid Power Solutions

Hybrid Power Solutions Inc. is a Canadian clean energy innovator listed on the Canadian Securities Exchange under the symbol "HPSS." The Company specializes in developing portable power systems that eliminate the need for fossil fuels in off-grid and remote applications. With a focus on environmental responsibility and technological innovation, Hybrid Power Solutions is committed to leading the clean energy transition.

On Behalf of the Company,

Francois Byrne, CEO and Director

For further information, inquiries, or media opportunities, please contact:

Hybrid Power Solutions

E: [email protected]

T: 866-549-2743

www.investhps.com

Investor Relations

Dean Stuart

E: [email protected]

T: 403-617-7609

Forward-Looking Statements

Certain information contained herein constitutes "forward-looking information" under Canadian securities legislation. Generally, forward-looking information can be identified by terminology such as "will," "expects," "anticipates," or variations of such words and phrases, or by statements that certain actions, events, or results "will" occur. Forward-looking statements are based on management’s estimates as of the date such statements are made and are subject to risks, uncertainties, and other factors that may cause actual results to differ materially from those expressed or implied by such statements.

The Canadian Securities Exchange does not accept responsibility for the adequacy or accuracy of this release.

The pizza leader is showing revitalized momentum. But are shares cheap enough?

After a monster run in the 2010s, Domino's Pizza (DPZ -0.23%) hasn't delivered much over the last half-decade. Including dividends, the pizza delivery specialist's five-year total return is roughly 10% -- essentially flat when stacked against inflation -- and quite disappointing when compared against the broader market's gains. Meanwhile, the underlying business has continued to expand its footprint, modernize the brand, and lean into delivery and carryout economics. The question for investors is whether recent progress is enough to turn a sideways stock into an attractive buy.

There are some positive signs. Domino's started 2025 with softer U.S. trends, then posted a better second quarter, helped by product introductions, broader distribution on delivery apps, and steady international growth. That improved cadence sets the stage for the rest of the year. But given where the stock trades, it will probably still take more than "better" to make the shares compelling.

Image source: Getty Images.

Momentum is improving
The most recent quarter shows progress in two key areas: sales and operations. In the second quarter of 2025, Domino's reported U.S. same-store sales growth of 3.4%, with international comps up 2.4% (currency-neutral). Total revenue rose 4.3% to about $1.15 billion, and income from operations increased nearly 15%, aided by strong franchise royalties and supply chain throughput. Management also pointed to healthy unit economics and robust advertising support as the company fully rolled out on the two largest delivery aggregators and expanded its menu, including stuffed crust.

"In the U.S., both delivery and carryout grew, driving meaningful market share gains," Domino's CEO Russell Weiner said alongside the report, adding that the business is "well-positioned" with more tools than ever to drive long-term value.

The bounce-back followed a choppy first quarter in which U.S. comps dipped 0.5% and the system posted a small net store decline (driven by international closures). Even there, though, international comps grew 3.7% (currency-neutral), and growth in franchise royalties and supply chain revenue supported the top line. The sequential improvement from Q1 to Q2 -- both in comps and operating income -- matters more than a single quarter's print and suggests promotional cadence, menu news, and aggregator awareness are gaining traction.

Looking ahead, two strategic levers look durable.

First, access via third-party apps broadens the funnel for occasional customers while keeping the core Domino's digital stack intact for loyal buyers; management now has both Uber's (UBER 1.08%) Uber Eats and DoorDash (DASH 3.82%) live at national scale.

Second, value and innovation continue to attract traffic; rewards program enhancements and items like parmesan-stuffed crust provide the brand with fresh reasons to be in the consideration set without relying solely on price. Those moves helped delivery comps turn positive in Q2.

Valuation and risks
Despite good underlying performance and massive underperformance for the stock over the last five years, the pizza delivery king isn't a clear buy. As of this writing, Domino's stock has a price-to-earnings ratio of about 25 -- about in line with its historical average multiple. Sure, 25 isn't particularly high for a high-return, asset-light franchisor, but it does limit returns if growth slows or margins compress.

Further, there are some key risks. Cost inputs and store-level labor, for instance, can pressure company-owned store margins. Indeed, this key profitability metric was down two full percentage points, year over year, in Q2. Additionally, international expansion -- one of Domino's biggest catalysts over the last few decades -- has seen pockets of volatility, including net closures earlier this year. Finally, while aggregators expand reach, they can complicate ticket dynamics and the customer experience if not managed carefully. Of course, none of these are new issues for Domino's. But they help explain why a price-to-earnings ratio of 25 isn't necessarily cheap.

So, is it finally time to buy? The investment case rests on steady mid-single-digit same-store growth, continued net unit additions, and operating-income expansion as supply chain and franchise royalty dollars grow with retail sales. If Domino's can sustain the Q2 trajectory -- positive delivery and carryout comps, healthy international trends, and incremental traffic from aggregators -- the current mid-20s price-to-earnings ratio may prove reasonable. But if momentum fades back toward flat U.S. comps or international volatility intensifies, that valuation could look full.

For investors interested in the stock, despite the risks, a measured approach makes sense. With trends improving, Domino's looks like a decent stock idea -- just not a clear bargain. A small starter position, with an eye toward adding on market or company-specific pullbacks, could be a sensible way to participate while giving the story room to prove it can compound again.

Daniel Sparks and his clients have no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Domino's Pizza, DoorDash, and Uber Technologies. The Motley Fool has a disclosure policy.

Analyst’s Disclosure:I/we have a beneficial long position in the shares of MU either through stock ownership, options, or other derivatives. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

Seeking Alpha's Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

A Boeing logo is seen before the opening of the 55th International Paris Airshow at Le Bourget Airport near Paris, France, June 13, 2025. REUTERS/Benoit Tessier/File Photo Purchase Licensing Rights, opens new tab

Sept 29 (Reuters) - Boeing

(BA.N), opens new tab is in the early stages of developing a new single-aisle airplane that would eventually replace the 737 MAX, the Wall Street Journal reported on Monday, citing people familiar with the matter.

Earlier this year, CEO Kelly Ortberg met with officials from Rolls-Royce Holdings

(RR.L), opens new tab in the UK to discuss a new engine for the aircraft, according to the WSJ report.

Sign up here.

The U.S. planemaker has also been designing the flight deck of a new narrow-body aircraft, the report said, adding that development remains in the early planning phase, with final decisions yet to be made.

Reuters could not immediately confirm the report. Boeing and Rolls-Royce did not immediately respond to a Reuters' request for comment.

The 737 MAX entered service in 2017, but the model was grounded globally in 2019 following two fatal crashes.

Reporting by Nilutpal Timsina in Bengaluru; Editing by Sherry Jacob-Phillips

Our Standards: The Thomson Reuters Trust Principles., opens new tab

This summer, the monster toy Labubu charmed the world with its cute and chaotic energy, commanding resale markups that would make day traders or Rolex flippers blush. Now, there are signs that the secondary market is losing steam — scalpers are panic-selling, watching prices crater by half or more.

The deal put it at the forefront of AI-powered commerce.

PayPal (PYPL 3.51%) has been trying to turn around its business for years, but its new partnership with Alphabet (GOOGL -1.03%) (GOOG -1.17%) has the potential to be a game-changer. With this partnership, it will change now be at the forefront of artificial intelligence (AI)-powered commerce.

As part of the deal, PayPal will become the primary payments processor across Google Cloud, Google Ads, and Google Play. Its branded checkout and payment services will also be incorporated throughout Google's broader ecosystem. But that's not all. PayPal will also migrate its entire technology stack to Alphabet's cloud computing platform, Google Cloud. That lets it ditch some of its legacy infrastructure and lean on Google's machine learning to help boost things like fraud detection and speed up transaction processing.

The two companies are also teaming up to create what they are calling "agentic commerce." This is where AI shopping agents will be able to help consumers not only make purchases, but also discover new products and comparison shop. The companies will also help develop AI agent standards and best practices. This is where e-commerce appears to be heading, and PayPal has positioned itself well for this future by teaming with Alphabet.

The partnership should also help PayPal expand its reach at a relatively low incremental cost. Integrating its payment platform across Google products brings it access to billions of users and millions of merchants without PayPal having to spend heavily on customer acquisition.

Image source: Getty Images.

In the past, CEO Alex Chriss has talked about not chasing low gross margin volume for the sake of revenue growth. Now, the economics of payment processing for a client as large as Google isn't going to be robust, but the sheer size of that volume and the technological partnership more than make this deal worthwhile. Meanwhile, moving more of PayPal's workload to Google Cloud should help it launch new features faster.

Why the stock is a buy
While there is still plenty of heavy lifting for PayPal to do, this deal should help the company achieve its goal of accelerating its branded checkout growth from the mid-single digits to between 8% to 10% by 2027, as its branded checkout is expanded to key Google properties.

Investors also should not underestimate the strategic importance of the partnership. For years, PayPal has faced criticism that it was stuck as just a digital wallet with little differentiation. Now it is embedding itself in one of the most influential tech ecosystems while also collaborating on the very protocols that will shape how AI shopping agents transact. That's a very different positioning than being yet another online checkout button.

It's also worth noting that PayPal continues to execute on other fronts. Venmo revenue grew more than 20% last quarter, and Pay with Venmo transactions were up 45%. Physical debit and credit cards are also gaining traction, with 2 million first-time PayPal and Venmo debit card users added in the U.S. in Q2. Transaction volume from those offline channels rose 8%. These aren't headline-grabbing innovations, but they show the company is broadening its user base and strengthening ties with consumers.

The stock has been a laggard, down roughly 20% year to date, even after posting strong earnings last quarter and raising its full-year EPS outlook. That has left PayPal at an attractive valuation, trading at a forward price-to-earnings ratio (P/E) of about 11.5 times 2026 analyst estimates.

There is a risk that the market won't immediately reward the partnership, since most of the financial benefit will take time to materialize, but for investors willing to be patient, this looks like the kind of strategic move that can reinvigorate growth and help close the gap between PayPal's valuation and its potential. AI-driven commerce is still in its early innings, and PayPal is now much better positioned than it was just a couple of months ago.

Geoffrey Seiler has positions in Alphabet and PayPal. The Motley Fool has positions in and recommends Alphabet and PayPal. The Motley Fool recommends the following options: long January 2027 $42.50 calls on PayPal and short September 2025 $77.50 calls on PayPal. The Motley Fool has a disclosure policy.