Market Signal Briefing

NEW YORK, Oct. 12, 2025 (GLOBE NEWSWIRE) --

WHY: Rosen Law Firm, a global investor rights law firm, reminds purchasers of securities of Semler Scientific, Inc. (NASDAQ: SMLR) between March 10, 2021 and April 15, 2025, both dates inclusive (the “Class Period”), of the important October 28, 2025 lead plaintiff deadline in the securities class action first filed by the Firm.

SO WHAT: If you purchased Semler Scientific securities during the Class Period you may be entitled to compensation without payment of any out of pocket fees or costs through a contingency fee arrangement.

WHAT TO DO NEXT: To join the Semler Scientific class action, go to https://rosenlegal.com/submit-form/?case_id=39889 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email [email protected] for information on the class action. A class action lawsuit has already been filed. If you wish to serve as lead plaintiff, you must move the Court no later than October 28, 2025. A lead plaintiff is a representative party acting on behalf of other class members in directing the litigation.

WHY ROSEN LAW: We encourage investors to select qualified counsel with a track record of success in leadership roles. Often, firms issuing notices do not have comparable experience, resources, or any meaningful peer recognition. Many of these firms do not actually litigate securities class actions, but are merely middlemen that refer clients or partner with law firms that actually litigate the cases. Be wise in selecting counsel. The Rosen Law Firm represents investors throughout the globe, concentrating its practice in securities class actions and shareholder derivative litigation. Rosen Law Firm achieved the largest ever securities class action settlement against a Chinese Company at the time. Rosen Law Firm was Ranked No. 1 by ISS Securities Class Action Services for number of securities class action settlements in 2017. The firm has been ranked in the top 4 each year since 2013 and has recovered hundreds of millions of dollars for investors. In 2019 alone the firm secured over $438 million for investors. In 2020, founding partner Laurence Rosen was named by law360 as a Titan of Plaintiffs’ Bar. Many of the firm’s attorneys have been recognized by Lawdragon and Super Lawyers.

DETAILS OF THE CASE: According to the lawsuit, defendants throughout the Class Period made materially false and/or misleading statements and/or failed to disclose that: (1) Semler Scientific did not disclose a material investigation by the United States Department of Justice (the "DOJ") into violations of the False Claims Act, while discussing possible violations of the False Claims Act (and aggressive DOJ enforcement thereof) in hypothetical terms; and (2) as a result, defendants' public statements were materially false and/or misleading at all relevant times. When the true details entered the market, the lawsuit claims that investors suffered damages.

To join the Semler Scientific class action, go to https://rosenlegal.com/submit-form/?case_id=39889 or call Phillip Kim, Esq. toll-free at 866-767-3653 or email [email protected] for information on the class action.

No Class Has Been Certified. Until a class is certified, you are not represented by counsel unless you retain one. You may select counsel of your choice. You may also remain an absent class member and do nothing at this point. An investor’s ability to share in any potential future recovery is not dependent upon serving as lead plaintiff.

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Attorney Advertising. Prior results do not guarantee a similar outcome.

-------------------------------

Contact Information:

        Laurence Rosen, Esq.
        Phillip Kim, Esq.
        The Rosen Law Firm, P.A.
        275 Madison Avenue, 40th Floor
        New York, NY 10016
        Tel: (212) 686-1060
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        www.rosenlegal.com

Investors should focus on companies offering advanced packaging and power management solutions to AI data centers.

Artificial intelligence (AI) is no longer just a technology megatrend. It is transforming how we live, work, learn, and play, and is reshaping the world as we know it.

However, training and running the advanced AI models that drive this transformation requires a massive amount of compute capacity and data bandwidth. Subsequently, the demand for the cutting-edge chips, servers, networking gear, and power systems needed to build massive data center capacity has skyrocketed.

Image source: Getty Images.

Nvidia's graphics processing units (GPUs) are being used extensively to enable accelerated computing in AI data centers. Broadcom is also helping these chips communicate efficiently with custom networking and connectivity solutions. But AI isn't only about semiconductors. It also depends on reliable chip packaging, as well as power management systems to make these high-performance servers function efficiently and reliably.

Here are two prominent yet lesser-known companies driving this gold rush from chips to power grids.

Amkor Technology
Amkor Technology's (AMKR -7.87%) advanced packaging and testing solutions also play a crucial role in the semiconductor manufacturing ecosystem. The company is the second-largest outsourced semiconductor assembly and test (OSAT) player globally. It assembles, packages, and validates GPUs, application-specific integrated circuits (ASICs), and high-bandwidth memory (HBM) chips used in accelerated computing platforms. These services ensure the performance and reliability of AI and high-performance computing chips.

In the second quarter of fiscal 2025, Amkor's revenue was up 3% year over year to $1.5 billion, while earnings per share (EPS) were $0.22. The company's gross margin was just 12% due to increased preparation costs for upcoming product ramps and headwinds from the early stage scale-up of the high-volume manufacturing facility in Vietnam. Those margin headwinds, however, are temporary.

While Amkor's financial growth doesn't seem explosive, there are still many reasons to keep an eye on the company. The global advanced packaging market is estimated to grow from $48.5 billion in 2023 to $119.4 billion in 2032. This appears to be a conservative estimate, considering the massive demand for AI chips in data centers worldwide.

Amkor continues to strengthen its position in advanced packaging technologies. The company offers advanced packaging solutions, including 2.5D and High-Density Fan-Out (HDFO), that facilitate efficient integration of high-bandwidth memory (HBM) in next-generation computing chips. The next-generation HDFO product has already entered high-volume production for a lead customer.

HDFO helps minimize signal loss and enables high-bandwidth communication between densely integrated, AI-optimized chips. The company's advanced packaging and testing lines in South Korea and Taiwan are working at high utilization levels. Amkor plans to expand capacity at these facilities further.

Amkor carried $2 billion in cash and $3.1 billion in total liquidity, while its total debt was $1.6 billion as of the end of the second quarter. With a debt-to-EBITDA ratio of around 1.5, Amkor maintains sufficient financial flexibility to invest in future growth initiatives.

Amkor trades at almost 20 times forward earnings, which is very reasonable. Coupled with its significant exposure to AI-driven packaging and testing demand, the company seems like a worthwhile pick now.

Vertiv Holdings
Vertiv Holdings (VRT 0.13%) has emerged as a key player in the development of AI infrastructure. The company provides the critical power and thermal management infrastructure needed to operate AI data centers at scale.

Its liquid-cooling franchise has scaled capacity over 40 times since 2024, driven by surging demand from hyperscalers for high-density server racks with larger power utilization. By dissipating the intense heat generated in these high-power AI servers, liquid-cooling systems enhance energy efficiency and minimize performance degradation due to overheating.

Vertiv's financial performance has been impressive. The company's net sales were up 35% year over year to over $2.6 billion in the second quarter. The company's backlog also soared 21% to $8.5 billion. This highlights the company's exceptional revenue visibility for 2025. Vertiv is now guiding for net sales of $10 billion and adjusted diluted earnings per share (EPS) guidance of $3.80 for this year. Management is also targeting an adjusted operating margin of 20% in 2025 and 25% by 2029.

Vertiv is increasingly helping link the power and thermal systems (gray space ) with IT hardware and racks (white space) in the data center. The acquisition of Great Lakes has added data rack enclosures, custom racks, and enhanced cable management solutions to Vertiv's portfolio. This deal has further strengthened Vertiv's capabilities to integrate white space and gray space in data centers.

The company has also strengthened its capabilities for AI-powered monitoring and control of its power and cooling infrastructure by acquiring Waylay NV. Hence, the company is well-positioned to deliver fully integrated and prefabricated systems to hyperscalers, enabling rapid expansion of data center capacity.

Vertiv has collaborated with CoreWeave and Dell Technologies to deploy Nvidia's latest Blackwell architecture-based GB300 NVL72 system. Its alliance with Oklo can help data centers access advanced nuclear power plants. Vertiv's nuclear power plant technology can help data centers manage their long-term energy demands in a cost-efficient manner. All this highlights that the company is at the forefront of AI infrastructure development.

Vertiv expects to generate adjusted free cash flow of $1.4 billion in fiscal 2025. With $2.5 billion in liquidity and net leverage (total debt to earnings) of only 0.6x, the company has ample flexibility to fund future growth initiatives both organically and inorganically.

Trading at almost 33.4 times forward earnings, Vertiv shares are not cheap. However, the premium valuation is justified considering the solid demand for its power and thermal management solutions in the global AI buildout. Hence, the stock can be a smart pick now.

Manali Pradhan has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Nvidia. The Motley Fool recommends Broadcom. The Motley Fool has a disclosure policy.

These stocks could explode as they unleash nuclear and rare-earth power.

Some stocks have the potential to deliver extraordinary returns over time. They generally fall into two camps: established players with wide economic moats and growth catalysts, or young companies in red-hot industries that are just starting to take off.

I have identified one compelling stock from each category that looks particularly attractive right now, thanks to the potential for extreme growth in nuclear energy and mining for rare earth minerals. Buying these stocks now and holding them for 5 to 10 years could generate monster returns.

Image source: Getty Images.

This miner for rare-earth elements is taking off
Rare earth elements are all the rage now. They're vital for several key industries such as electric vehicles (EVs), semiconductors, electronics, wind turbines, and medical imaging. Their importance was already well known, but the renewed interest in the stock of rare-earth element miners is largely credited to President Donald Trump's policies targeting supply chains for crucial materials.

Currently, 80% of the rare earth elements consumed in the U.S. are imported, with 77% coming from China. The Trump administration is going all-in to reduce this reliance for such crucial materials, buying stakes in companies to fuel domestic mining and production of rare earth elements.

One rare earth miner whose stock is turning out to be a monster that could be the next Trump target is USA Rare Earth (USAR 4.89%). The stock has soared 250% in just the past three months, and it could rally even higher.

While there are several companies mining for rare earth minerals, USA Rare Earth is a vertically integrated mining-to-magnets company. Simply put, it mines rare earth minerals and manufactures magnets, the end-use products that go into EV motors, hard disc drives, wind turbine generators, MRI machines, and defense and aerospace equipment.

USA Rare Earth holds mining rights to the Round Top Mountain deposit in Texas, but is currently focused on building a rare earth magnet plant in Stillwater, Oklahoma. It expects to begin production as early as next year and is acquiring U.K.-based LCM for $100 million in cash and $6.74 million in stock to scale up production to a full capacity of 5,000 metric tons. LCM's output will be used as feedstock at Stillwater.

USA Rare Earth's new CEO, Barbara Humpton, recently said in a CNBC interview that the company is in close communication with the Trump administration for a potential deal. In July, the U.S. Department of Defense struck a deal to acquire a 15% stake in another producer of rare earth elements, MP Materials (MP 8.69%).

With China recently imposing more-stringent export controls on these raw materials, there's an even bigger incentive for the U.S. government to push domestic miners. With USA Rare Earth already signing up several customers and expecting its first magnet sales next year, the stock could generate explosive returns in the long term.

This stock has surged 800% in 5 years
Nuclear energy stocks are on fire, powered by soaring demand for electricity from artificial intelligence (AI) data centers that require enormous amounts of power to keep their servers and cooling systems running around the clock. The International Energy Agency (IEA) projects that global demand for electricity to power data centers will more than double by 2030, surpassing the entire electricity consumption of Japan today.

President Trump has further fueled interest in nuclear energy and uranium stocks by signing multiple orders to expedite the build-out of nuclear reactors and uranium fuel supplies. Nuclear reactors run on uranium fuel, and the U.S. imports 99% of the uranium concentrate used to make nuclear fuel.

The two catalysts present huge growth opportunities for the nuclear power and uranium industries, and one company sitting prominently at the forefront is Canada-based Cameco (CCJ -0.09%), one of the largest uranium miners in the world.

Shares of Cameco had already generated monster returns well before investors caught up with nuclear energy stocks in 2025. The stock has more than doubled in the past six months.

CCJ data by YCharts.

Cameco sells uranium concentrate and fuel services directly to nuclear power utilities in 16 countries under long-term contracts. It also owns a 49% stake in Westinghouse Electric Company, a supplier of technology, equipment, and services for the nuclear power sector. That makes Cameco a top play in two crucial sections of the nuclear energy industry: nuclear fuel, and construction and maintenance of nuclear power plants.

Given the persistently low level of long-term uranium contracting, Cameco believes utilities will have to secure significant amounts of uranium -- in the billions of pounds -- to meet their fuel requirements through 2045. That should set the stage for explosive growth for Cameco and its stock in the coming years. The company has also paid a dividend every year since going public in 1991.

Neha Chamaria has no position in any of the stocks mentioned. The Motley Fool recommends Cameco and MP Materials. The Motley Fool has a disclosure policy.

The available evidence suggests this supercharged growth stock could announce its first stock split in more than a decade at some point over the coming year.

The Nasdaq Composite has been on a relentless run over the past few years and continues to notch new highs. The tech-centric index rose 43% in 2023, 29% in 2024, and has risen 18% thus far in 2025 (as of this writing). This trifecta bodes well for the coming year, as history suggests there could be more to come.

There have been five bull markets over the past 50 years that stretched beyond three years. In each of those cases, the market continued to climb, according to data compiled by Ryan Detrick, chief market strategist at financial services company Carson Group. His research shows that bulls that made it past their third birthday continued to rally, lasting eight years on average, with the shortest clocking in at five years and the longest running into double digits.

One contributing factor to the lofty market has been a resurgence in the popularity of stock splits over the past few years. This trend has prompted investors to take a fresh look at companies with impressive growth stories and high sticker prices, which are historically a precursor to a stock split. One such company is Netflix (NFLX -0.96%). The streaming video stock has surged more than 1,000% over the past decade (as of this writing), obliterating the 280% gains of the Nasdaq. The company's recent performance suggests there could be more to come.

Image source: Getty Images.

Bullish results
In the second quarter, Netflix reported results that surpassed expectations across the board. Revenue of $11 billion climbed 16%, driving diluted earnings per share (EPS) up 47% to $7.19. Management cited subscription price hikes, strong subscriber growth, and increasing ad revenue for driving the robust top-line growth. Increases in profitability came thanks to higher sales and lower expenses.

Perhaps as importantly, management is predicting its growth streak will continue. Netflix is guiding for third-quarter revenue of $11.5 billion, up 17%, while EPS of $6.87 would increase roughly 27%.

Management cited several factors that contributed to Netflix's bullish growth in Q2:

Squid Games 3 became the company's third biggest season of any series in the company's history, taking up residence behind seasons 1 and 2.
KPop Demon Hunters quickly became a global sensation, becoming not only Netflix's most-watched animated film, but Netflix's most popular film ever. It also spawned sold-out sing-along showings in theaters, while becoming the first soundtrack with four simultaneous top-10 songs on the Billboard Hot 100.
The Katie Taylor vs. Amanda Serrano boxing match became the "most-watched professional women's sporting event of 2025."

This could be just the beginning, as the company has a strong slate of content touching down in the second half of the year. The debut of the second season of Wednesday has already smashed records, with 50 million views in its first four days, and amassing more than 95 million views since its early September release. Let's not forget the highly awaited finale of Stranger Things, which will be released in three parts during the holiday season.

Netflix is also leaning into the success of its live events. The Terence Crawford vs. Canelo Alvarez boxing match was a resounding success, attracting more than 41 million views. The company will host two NFL games on Christmas Day 2025: The Dallas Cowboys vs. the Washington Commanders, and the Detroit Lions vs. the Minnesota Vikings, both of which will stream live on Netflix to bring Christmas cheer to sports fans.

Finally, advertising might well be the company's biggest growth driver going forward. At an industry conference earlier this year, Netflix revealed that the advertising tier accounted for 55% of new subscribers where it's offered, and users for the Standard with Ads tier increased 30% quarter over quarter -- which helps illustrate the magnitude of the opportunity.

The stock-split wildcard
With a stock price of $1,191 (as of this writing), Netflix is among the priciest stocks listed on the Nasdaq. Additionally, this isn't the company's first rodeo. The streaming pioneer conducted a 2-for-1 stock split in February 2004. A second 7-for-1 split came roughly a decade later in July 2015. So the timing is right.

While the company hasn't announced any intention to split its shares, with a current stock price above $1,000, it certainly qualifies. Furthermore, given the resurgence in stock splits, I believe it's only a matter of time.

There's a widely held belief that stock splits are a nothing burger, as they don't change any of the underlying fundamentals of the company. While that's true, it turns out the reality is more nuanced. The robust business performance that led to the stock split typically continues, driving further increases in the stock price. Research reveals that companies that conduct a stock split return 25%, on average, in the year following the announcement, more than double the 12% average return for the S&P 500, according to Bank of America analyst Jared Woodard.

At roughly 37 times expected 2026 earnings, Netflix might appear expensive at first glance. However, as its history illustrates, investors continue to underestimate the streaming giant. Furthermore, given its ability to find new avenues of growth, I'd argue that's a fair price. That's why 2026 could be another banner year for Netflix shareholders -- stock split or not.

Bank of America is an advertising partner of Motley Fool Money. Danny Vena has positions in Netflix. The Motley Fool has positions in and recommends Netflix. The Motley Fool has a disclosure policy.

The automaker is on a relentless quest for groundbreaking technological advancements.

Electric vehicle (EV) manufacturer Tesla (TSLA -4.97%) achieved fame and fortune after its Model S car came out in 2012. The automobile not only boosted the company's ascent, but the entire EV market as well.

The Model S showed what was possible with an electric car. From the ability to travel long distances to a self-driving mode, the vehicle broke the mold in terms of the public's perception of an EV. I thought it was a game-changer at the time, and that's why I bought the car, as well as Tesla stock.

Now, the company is racing to repeat its Model S success. This time, it's a different type of auto, as in the automated kind. And while artificial intelligence is part of the equation, the next groundbreaking achievement isn't just about AI. It's what the company calls "sustainable abundance."

Image source: Tesla.

What Tesla means by "sustainable abundance"
Tesla periodically publishes a master plan describing long-term goals. In the latest version, the company outlined its future vision, stating, "This next chapter in Tesla's story will help create a world we've only just begun to imagine and will do so at a scale that we have yet to see."

Tesla predicts a future where technology is used sustainably to create boundless prosperity for all, a concept it describes as "sustainable abundance." The idyllic aspiration may sound appealing, but how can it be achieved in practical terms?

As a step toward its ambition, the company stated, "We are building the products and services that bring AI into the physical world." One example is its robotaxi service, which Tesla launched in June as a pilot program in Austin.

This program uses a modified version of its Model Y vehicles to start. Over the long run, Tesla intends to construct an AI-driven car with no steering wheel called the Cybercab.

The company plans to produce a fleet of Cybercabs in 2026 using its innovative "unboxed" manufacturing strategy. This vehicle construction technique employs several modular assembly lines rather than being constrained to a single, linear process.

How Tesla is pulling together its long-term vision
Self-driving cars are only the beginning. Tesla is building humanoid robots controlled by AI. The idea is that these robots will provide labor for dangerous or monotonous work, freeing up time for people to pursue more enjoyable endeavors.

Another piece of the company's vision is the sustainable aspect. For this, Tesla looks to its solar energy business. This segment saw a stupendous 67% year-over-year sales growth in 2024, contributing $10.1 billion of the company's $97.7 billion. However, through the first half of 2025, revenue growth in this area has slowed, reaching $5.5 billion compared to $4.6 billion last year.

Of course, Tesla's far-reaching objectives will take years to accomplish, and 2025 was a tough one for several reasons. Business performance was hindered by macroeconomic factors, which include tariffs combined with a drop in Tesla's popularity due to the actions of its divisive CEO, Elon Musk.

That said, the company managed to achieve a record number of vehicle deliveries and energy storage product deployments in the third quarter, although that's likely due to consumers rushing to take advantage of federal EV tax credits before they expired in September. Full business performance details will be unveiled on Oct. 22, when it's scheduled to release its Q3 earnings report.

Is now the time to buy Tesla stock?
Tesla's Model S launch demonstrated its ability to deliver technological innovation and execute on goals others thought unattainable. Its "sustainable abundance" plan is even more ambitious, but perhaps it can repeat the Model S feat.

The company's vision of a futuristic world with AI, autonomous vehicles, and humanoid robots has the potential to fundamentally change society. But Tesla must advance its robotaxi service as an initial step on this path.

If that proves successful, Tesla stock could skyrocket. In fact, shares are up around 80% over the past 12 months through Oct. 8. Yet as a result, its share price valuation has soared.

This chart looks at Tesla stock's price-to-earnings (P/E) ratio, which indicates the amount investors are prepared to pay for each dollar of earnings over the trailing 12 months, revealing it's higher in October than it's been over the past year.

Data by YCharts.

With a P/E multiple of around 250, Tesla stock is quite expensive. The sky-high valuation creates risk when investing in shares right now.

If you believe in Tesla's vision and that the company can achieve success with its robotaxi service and robots out of a sci-fi movie, then the prudent approach is to wait for the share price to drop before deciding to invest.

Robert Izquierdo has positions in Tesla. The Motley Fool has positions in and recommends Tesla. The Motley Fool has a disclosure policy.

October 12, 2025 13:17 ET

 | Source:

PyroGenesis Inc.

MONTREAL, Oct. 12, 2025 (GLOBE NEWSWIRE) -- PyroGenesis Inc. (“PyroGenesis” or “the Company”) (TSX: PYR) (OTCQX: PYRGF) (FRA: 8PY1), the leader in innovating for ultra-high temperature processes and engineering, and a technology provider to heavy industry & defense, provides the following comment in regard to a recent online post from a current member of the Company’s board of directors.

On Saturday October 11, 2025, it came to the Company’s attention that an online post from a current member of the PyroGenesis board of directors had been made on the night of Friday October 10, outside of market hours. This post contained information regarding the Company’s recently announced non-brokered private placement (the “private placement”). A portion of this information should not have been posted and is incorrect. Upon recognizing the error, the post was quickly deleted. PyroGenesis asks that any versions of this since-deleted post be disregarded and not disseminated further.

More specifically, the post contained details about the private placement that had been previously released, however it also contained a sentence that “… (the Company’s ongoing private placement) has been oversubscribed bringing in between $7.5-$8.0 million to the company…”.

While the Company had previously announced, on October 1, 2025, its intention to conduct this non-brokered private placement, with a potential funding of approximately $5 million, the private placement is currently ongoing, and neither a statement of oversubscription, nor a suggestion that the private placement is complete, can be formally, nor accurately, stated at this time.

As a matter of clarification, the Company can state that, at the time of this press release, the private placement is not officially oversubscribed. We can further confirm that the first tranche of the first unit group of the private placement, is expected to be completed during the upcoming week.

PyroGenesis is committed to timely disclosure and takes corporate governance seriously. The board of directors has reviewed this situation in full, and corrective action has been taken.

About PyroGenesis Inc.

PyroGenesis leverages 30 years of plasma technology leadership to deliver advanced engineering solutions to energy, propulsion, destruction, process heating, emissions, and materials development challenges across heavy industry and defense. Its customers include global leaders in aluminum, aerospace, steel, iron ore, utilities, environmental services, military, and government. From its Montreal headquarters and local manufacturing facilities, PyroGenesis’ engineers, scientists, and technicians drive innovation and commercialization of energy transition and ultra-high temperature technology. PyroGenesis’ operations are ISO 9001:2015 and AS9100D certified, with ISO certification maintained since 1997. PyroGenesis’ shares trade on the TSX (PYR), OTCQX (PYRGF), and Frankfurt (8PY1) stock exchanges

Cautionary and Forward-Looking Statements

This press release contains “forward-looking information” and “forward-looking statements” (collectively, “forward-looking statements”) within the meaning of applicable securities laws. In some cases, but not necessarily in all cases, forward-looking statements can be identified by the use of forward-looking terminology such as “plans”, “targets”, “expects” or “does not expect”, “is expected”, “an opportunity exists”, “is positioned”, “estimates”, “intends”, “assumes”, “anticipates” or “does not anticipate” or “believes”, or variations of such words and phrases or state that certain actions, events or results “may”, “could”, “would”, “might”, “will” or “will be taken”, “occur” or “be achieved”. In addition, any statements that refer to expectations, projections or other characterizations of future events or circumstances contain forward-looking statements. Forward-looking statements are not historical facts, nor guarantees or assurances of future performance but instead represent management’s current beliefs, expectations, estimates and projections regarding future events and operating performance.

Forward-looking statements are necessarily based on a number of opinions, assumptions and estimates that, while considered reasonable by PyroGenesis as of the date of this release, are subject to inherent uncertainties, risks and changes in circumstances that may differ materially from those contemplated by the forward-looking statements. Important factors that could cause actual results to differ, possibly materially, from those indicated by the forward-looking statements include, but are not limited to, the risk factors identified under “Risk Factors” in PyroGenesis’ latest annual information form, and in other periodic filings that it has made and may make in the future with the securities commissions or similar regulatory authorities, all of which are available under PyroGenesis’ profile on SEDAR+ at www.sedarplus.ca. These factors are not intended to represent a complete list of the factors that could affect PyroGenesis. However, such risk factors should be considered carefully. There can be no assurance that such estimates and assumptions will prove to be correct. You should not place undue reliance on forward-looking statements, which speak only as of the date of this release. PyroGenesis undertakes no obligation to publicly update or revise any forward-looking statement, except as required by applicable securities laws.

Neither the Toronto Stock Exchange, its Regulation Services Provider (as that term is defined in the policies of the Toronto Stock Exchange) nor the OTCQX Best Market accepts responsibility for the adequacy or accuracy of this press release.

For further information contact [email protected] or visit http://www.pyrogenesis.com

Coupang is expanding from fast-growing e-commerce upstart to one of Asia's most important internet companies.

When investors think of Asian e-commerce, Coupang (CPNG -3.74%) often draws the "Amazon of South Korea" comparison. This label captures part of the story but not the whole picture.

Coupang is headquartered in Seattle and describes itself as a technology company. While it's best known for its retail dominance and hallmark Rocket Delivery service, it has also expanded into fintech, food delivery, streaming, and advertising. Still, e-commerce remains the foundation of its business -- and that's where most of its growth and profits are generated today.

The company has given shareholders plenty of reasons to be optimistic -- here are three of the biggest reasons investors are bullish on Coupang stock.

1.Coupang dominates South Korea's retail market
South Korea is one of the most attractive e-commerce markets in the world, thanks to its internet penetration rate of over 97% and a highly concentrated population around the capital city of Seoul. Against this backdrop, Coupang has emerged as the undisputed leader in this market with approximately 24 million active customers -- roughly 46% of South Korea's entire population.

The company's edge lies in logistics. Coupang has spent years building a dense fulfillment and delivery network, strategically placing warehouses so that 70% of South Koreans live within a seven-mile radius of a logistics center. This extensive logistics footprint allows its Rocket Delivery service to consistently meet its promise of "dawn delivery" and same-day fulfillment. Note that Coupang reported the 70% figure in its 2021 IPO filing, so the actual number today is likely to be even higher than that.

This network doesn't just offer customers unmatched convenience and service -- it's a moat for the business. Once customers grow accustomed to reliable, rapid delivery, switching to rivals like Naver becomes far less appealing. That customer loyalty bears out in Coupang's revenue per active customer, which increased from $1,196 in 2023 to $1,207 in 2024, reflecting a steady upward trend that suggests customers are spending more with the company over time.

2.Profitability is improving -- and fast
For years, Coupang was criticized for operating losses as it invested heavily in the business. But that narrative is shifting. In Q2 2025, Coupang reported $8.5 billion in revenue, a 16% year-over-year increase, with gross profit rising even faster at 20%. Net income hit $31 million, reversing a loss from the year-ago period. It has also been profitable for the last four consecutive quarters, suggesting this trend is sustainable.

That kind of momentum matters. It shows that Coupang is beginning to flex its scale -- higher volumes are driving operating leverage, while investments in automation and AI also contributed to better efficiency. Unlike growth companies that fail to exit the cash-burning phase, Coupang now has the flexibility to self-fund its international expansion and new initiatives.

The trajectory looks similar to Amazon's early era -- years of losses followed by margin expansion. Investors who once worried about red ink now see a business with strengthening financial discipline.

3. New markets and verticals expand Coupang's runway
While South Korea remains its foundation, Coupang isn't standing still. After entering the Taiwanese market just a few years ago, the company has already built an impressive growth machine.

In Q2 2025, revenue growth in Taiwan was in the triple-digits, and Coupang expects that rate to improve further in the third quarter. It is using the same playbook it refined at home: aggressive investment in logistics and customer experience to win loyalty.

While international expansion is costly, it's also necessary if Coupang wants to break the mold of a "single-market story." Success in Taiwan could serve as proof of concept for the company's broader expansion across Asia.

Beyond geography, Coupang is also expanding into new verticals like Coupang Eats (food delivery), fintech, and video streaming. These efforts remain small compared to its core commerce business, but they represent important optionality. If even one of these bets scales meaningfully, it could add another growth engine.

What it means for investors
Coupang is no longer just a fast-growing but unprofitable e-commerce upstart. It has matured into a diversified technology company with a dominant retail business in its home market, improving profitability, and bold ambitions in both international and adjacent markets.

For long-term investors, the central question is whether Coupang can replicate its success outside of South Korea and turn new verticals into meaningful opportunities. If it can do so, Coupang will cement itself as one of Asia's most important internet companies.

All said, investors should keep Coupang on their radar.

Lawrence Nga has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Amazon. The Motley Fool recommends Coupang. The Motley Fool has a disclosure policy.

Adoption of Datatrak's eClinical solution enables CRO to actively manage all clinical trial data, processes, and documents on a single platform and dashboard with the first true eSource solution that seamlessly integrates EDC, RTSM, eTMF, CTMS, eConsent, ePRO/eCOA, Imaging Data, Central and Local Labs, Data Imports and Exports, Enterprise level management of Workflows and Timelines. AUSTIN, TX / ACCESS Newswire / October 12, 2025 / Datatrak International (OTC:DTRK) announces that a large European CRO commits to Datatrak's eClinical Technology Platform for a fully integrated all-in-one clinical trial data solution for eSource, EDC, RTSM, eTMF, CTMS, eConsent, ePRO, Enteprise Management for Workflows and Timelines and other solutions.

Investing in a leading enterprise artificial intelligence (AI) company can prove to be a smart strategy in the next few years.

Shares of enterprise artificial intelligence (AI) giant Oracle (ORCL -1.33%) have surged nearly 74% so far in 2025. The company has benefited from the explosive demand for data center capacity, driven by the rapid expansion of AI infrastructure.

With its market capitalization sitting comfortably at $828.6 billion as of Oct. 6, the question now is whether Oracle can cross the coveted $1 trillion mark by 2028. Here's why this scenario seems highly possible.

Backlog conversion to revenues
Oracle ended the first quarter of fiscal 2026 (which ended Aug. 31) with exceptionally high remaining performance obligations (RPO) of $455 billion, up 359% on a year-over-year basis. The company has contracts with major AI companies, including OpenAI, xAI, Meta Platforms, Nvidia, and Advanced Micro Devices.

Oracle currently operates 34 multicloud data centers on Microsoft's Azure, Alphabet's Google Cloud, and Amazon's AWS infrastructure. Multicloud database revenues grew by 1,529% year over year in the first quarter. Since the hybrid cloud strategy appears to be working with enterprise customers, the company plans to build an additional 37 multicloud data centers by the end of fiscal 2026. The rapid capacity expansion highlights the company's plan to convert its record pipeline into revenue-generating workloads.

Management expects Oracle Cloud Infrastructure (OCI) revenues to jump 77% year over year to $18 billion in fiscal 2026 and become $73 billion in fiscal 2028. The overall cloud business accounted for nearly 48% of the company's total revenues in the first quarter. If Oracle successfully converts its backlog into revenues as projected, we can expect the overall cloud mix to exceed 50% of the company's total revenues. The improved revenue mix will translate into higher profit margins, which can help expand its valuation multiples and lead to higher share price gains.

AI Database
Oracle's recently launched AI Database can also prove to be a significant catalyst for the company's next phase of growth. This database can vectorize enterprise data (converting it into numbers or using algorithms to be stored and accessed efficiently), so that large language models can accurately process and reason over this data. It also allows secure connections with leading large language models.

These capabilities have opened up a massive inferencing opportunity for Oracle, as enterprises will increasingly opt to run complex AI models on proprietary datasets in a secure environment. Since Oracle is already the largest custodian of high-value private enterprise data worldwide, the AI database will further drive AI adoption among its clients.

Oracle is already a dominant player in the multitrillion-dollar AI training market. However, management expects the inferencing opportunity to prove even bigger than the training one.

Capacity expansion
Demand for Oracle's cloud infrastructure exceeds the available supply. Hence, the company has planned nearly $35 billion in capital expenditures (capex) for fiscal 2026, primarily for revenue-generating equipment in data centers. The company is already seeing customers consuming data center capacity within weeks of delivery. The urgency of AI demand and clear monetization potential further increase investor confidence.

Maintaining balance sheet strength
Oracle ended the first quarter with $11 billion in cash and marketable securities, $12 billion in short-term deferred revenue, and a strong operating cash flow of $8.1 billion. While free cash flow was temporarily negative due to heavy capex, this may soon improve as capacity deployments and backlog translate into billable workloads.

The company expects revenues to grow year over year by 16% in constant currency, and operating income to grow in the mid-teens percentage in fiscal 2026. The company is guiding for even stronger operating income growth in fiscal 2028.

Oracle's total debt was at $94 billion at the end of the first quarter. The company has also issued an additional $18 billion in bonds in late September, resulting in a pro forma debt load of approximately $112 billion. However, despite the high debt, Oracle still holds investment-grade credit ratings of Baa2 from Moody's and BBB from S&P Global.

Can Oracle enter the $1 trillion club?
To reach a market capitalization of $1 trillion in 2028, Oracle's market cap must increase by almost 21% (at the time of this writing). This is an achievable target if Oracle manages to convert backlog into revenue rapidly, bring new data center capacity online, and push adoption of its AI database.

Oracle must also combine its growth momentum with tight financial discipline. The company should focus on reducing leverage while also improving profitability and free cash flows.

In such a scenario, the company may easily maintain its elevated forward price-to-earnings (PE) ratio of 36.6x. Analysts expect the company's non-GAAP (generally accepted accounting principles) earnings per share (EPS) to be around $11.2 in fiscal 2028. This translates into a share price of around $409.9, which is over 40% higher than its close of $291.6 (on Oct. 6).

Hence, it is highly plausible for Oracle to enter the $1 trillion club by 2028.

Manali Pradhan has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Advanced Micro Devices, Alphabet, Amazon, Meta Platforms, Microsoft, Moody's, Nvidia, Oracle, and S&P Global. The Motley Fool recommends the following options: long January 2026 $395 calls on Microsoft and short January 2026 $405 calls on Microsoft. The Motley Fool has a disclosure policy.

The consumer price index will be delayed until next week as a result of the government shutdown, but the producer price index is still on track for release. And we'll see earnings from Wells Fargo, Morgan Stanley, ASML, and more.

Griffin isn't retreating from AI, but he had good reasons to take some profits and rebalance his bets on the trend.

Ken Griffin is not your typical Wall Street billionaire. As the founder and CEO of Citadel, he leads one of the most sophisticated and consistently profitable hedge funds in history. He has more than earned his reputation for being a rare blend of macro strategist and quantitative mastermind.

Citadel's second-quarter 13F form, which was filed in August, revealed a pair of notable moves: The hedge fund trimmed its position in data mining specialist Palantir Technologies (PLTR -5.39%) by 48% -- selling roughly 640,000 shares. That left Citadel with a stake that's today worth about $130 million. At the same time, the firm boosted its position in semiconductor powerhouse Nvidia (NVDA -4.84%) by a staggering 414% -- adding more than 6.5 million shares, and bringing its stake in it to around $1.5 billion at current share prices.

These moves speak volumes about Griffin's evolving view of the artificial intelligence (AI) landscape. Below, I'll unpack what might have influenced Citadel's decision-making, and what investors can conclude from this reshuffle.

Why Griffin trimmed Palantir: A rational hedge fund rebalance
On the surface, Citadel's decision to offload nearly half of its stake in Palantir may appear bearish. But in the world of hedge funds, selling doesn't always signal lost conviction -- it's often about managing risk.

Palantir's meteoric rise -- shares have soared by more than 2,000% over the past three years -- has left even its sincerest believers aware that the stock is priced for perfection. Trading at a price-to-sales ratio of 135, Palantir is flirting with valuations reminiscent of the dot-com era.

For disciplined managers like Griffin, emotion cannot override basic math. Hedge funds thrive by constantly reallocating their capital, which includes trimming their positions in their winners once they've run too far, too fast. Notably, famous investors like Stanley Druckenmiller and Cathie Wood have played this same hand with Palantir positions before.

In the grand scheme of things, taking some chips off the table from a high-flying stock is simply about risk-adjusted returns. Palantir's long-term fundamentals remain impressive, but hedge funds cannot afford to be sentimental. Locking in some profits gives them more financial flexibility to invest in opportunities that offer a better balance between upside and valuation.

Image source: Getty Images.

Why Citadel keeps buying Nvidia: The backbone of AI infrastructure
In my view, Citadel's growing position in Nvidia signals Griffin's conviction that the next decade of computing will be defined not by those who write algorithms, but by those who control the infrastructure that runs them.

Over the past few years, Nvidia has evolved into the world's preeminent supplier of accelerated computing hardware. Its GPUs now power everything from large language models (LLMs) and autonomous systems to next-generation humanoid robots.

But Nvidia's dominance isn't just about hardware -- it's about the ecosystem. The company's CUDA software platform has become a moat of its own, locking developers into a computing standard that few rivals can match.

Citadel's accumulation of Nvidia stock reflects several reinforcing trends:

Hyperscaler spending: Cloud infrastructure giants like Microsoft, Amazon, and Alphabet are collectively investing hundreds of billions of dollars annually to expand data center capacity.
Strategic integrations: Nvidia's partnerships with OpenAI, Intel, and Oracle are only beginning to realize their potential.
Relentless innovation: The company's forthcoming GPU architectures -- Blackwell Ultra and Rubin -- extend its technological lead and will keep its growth runway secure.

While Nvidia also trades at a premium valuation, its structural growth story remains unrivaled. As corporations and governments race to build AI infrastructure, Nvidia stands as the most reliable -- and arguably indispensable -- foundation for the AI era.

A masterclass in portfolio evolution
Griffin's moves signal a calculated rotation within the AI megatrend -- not a retreat from it. By trimming his stake in Palantir and doubling down on Nvidia, Citadel is effectively betting on where the next wave of outsize profits in AI will emerge.

The takeaway for investors is clear: Don't chase hype narratives or follow momentum. Instead, try to anticipate capital flows. Griffin isn't abandoning AI; he's rebalancing his bets on the trend toward the pick-and-shovel plays that are supporting it.

My take is that Griffin thinks Palantir's story is maturing, while Nvidia's machine is still poised to add muscle.

Adam Spatacco has positions in Alphabet, Amazon, Microsoft, Nvidia, and Palantir Technologies. The Motley Fool has positions in and recommends Alphabet, Amazon, Intel, Microsoft, Nvidia, and Palantir Technologies. The Motley Fool recommends the following options: long January 2026 $395 calls on Microsoft, short January 2026 $405 calls on Microsoft, and short November 2025 $21 puts on Intel. The Motley Fool has a disclosure policy.

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By Jonathan Ponciano
–
Oct 12, 2025 at 2:44PM

Key Points

Benson Investment Management acquired 73,875 shares of midstream service provider ONEOK for an estimated $5.4 million in the third quarter.

The position represents 1.8% of reportable assets under management.

The new position places ONEOK outside the fund’s top five holdings.

Benson Investment Management Company, Inc. initiated a new position in ONEOK (OKE -2.85%) in the third quarter with an estimated $5.4 million transaction, according to an SEC filing released on Friday.

What HappenedBenson Investment Management Company, Inc. reported a new stake of 73,875 shares in ONEOK (OKE -2.85%) in its latest quarterly disclosure to the Securities and Exchange Commission. The estimated transaction value of $5.4 million represented 1.8% of the fund’s $292.7 million in reportable U.S. equity holdings.

What Else to KnowTop holdings after the filing:

GLD: $14,681,622 (5% of AUM)GOOGL: $14,579,437 (5% of AUM)MSFT: $12,810,457 (4.4% of AUM)NVDA: $11,386,045 (3.9% of AUM)AMZN: $9,393,644 (3.2% of AUM)As of Friday, shares of ONEOK were priced at $69.09, marking a one-year decline of 29% and lagging well behind the S&P 500's 12% gain over the same period.

Company OverviewMetricValueRevenue (TTM)$28 billionNet Income (TTM)$3.1 billionDividend Yield6%Price (as of market close Friday)$69.09Company SnapshotONEOK, Inc. provides natural gas gathering, processing, storage, and transportation services, along with natural gas liquids (NGL) fractionation, storage, and distribution across the Mid-Continent and Rocky Mountain regions of the United States.The company leverages extensive midstream infrastructure and regulated pipeline assets to transport, store, and process natural gas and NGLs.Its main customers include integrated and independent energy producers, natural gas and NGL marketers, propane distributors, municipalities, and industrial end users such as petrochemical and refining companies.ONEOK, Inc. is a leading midstream energy company with a substantial footprint in natural gas and NGL infrastructure, operating over 17,500 miles of gathering pipelines and significant storage facilities. The company’s strategy focuses on essential energy infrastructure, supporting a competitive dividend yield. ONEOK’s scale, geographic reach, and integrated asset base enable it to serve producers and end users throughout major U.S. energy markets.

Foolish TakeBenson Investment Management’s new $5.4 million position in ONEOK adds exposure to energy infrastructure in a portfolio largely dominated by tech and metals. While the midstream operator’s shares have slid nearly 30% over the past year, Benson’s buy comes as the company posts strong underlying fundamentals and strong earnings growth.

In the second quarter of 2025, ONEOK reported net income of $853 million, up 9% year over year, and a 22% rise in adjusted EBITDA to roughly $2 billion, supported by higher volumes due largely to increased production in the mid-continent and Rocky Mountain regions. The firm is targeting $8 billion to $8.45 billion in full-year adjusted EBITDA and maintains a $4.12 annualized dividend, reinforcing its reputation as a stable, fee-based cash generator.

For Benson, ONEOK offers diversification and yield at a time when most top holdings—like Alphabet, Microsoft, and Nvidia—derive value from growth rather than income. The company next reports earnings on October 29.

Glossary13F reportable assets: Assets that institutional investment managers must disclose quarterly to the SEC, typically U.S. equity holdings.
Assets under management (AUM): The total market value of investments managed on behalf of clients by a fund or firm.
Dividend yield: Annual dividend payments divided by the stock price, expressed as a percentage.
Midstream infrastructure: Facilities and pipelines used to transport, store, and process oil and natural gas between production and end users.
NGL (Natural Gas Liquids): Hydrocarbon liquids such as propane, butane, and ethane separated from natural gas during processing.
Fractionation: The process of separating mixed natural gas liquids into individual products like ethane, propane, and butane.
Trailing twelve months (TTM): The 12-month period ending with the most recent quarterly report.
New position: A security or asset newly purchased by an investor or fund, not previously held in the portfolio.
Integrated asset base: A network of interconnected facilities and infrastructure supporting a company’s operations across the value chain.
Quarterly disclosure: Regular report filed every three months detailing a fund’s holdings and financial activities.

About the Author

Jonathan Ponciano is a contributing stock market analyst at The Motley Fool. He has nearly a decade of experience as a financial journalist, most recently as an editor and senior reporter at Forbes focused on markets, technology, and entrepreneurship. Jonathan has also written for Investopedia and the Los Angeles Business Journal. He holds a dual B.A. in Business Journalism and Economics from the University of North Carolina at Chapel Hill and an M.B.A. from Columbia Business School. A North Carolina native now based in New York City, Jonathan has also lived in Mexico City and Los Angeles.

Jonathan Ponciano has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Alphabet, Amazon, Microsoft, and Nvidia. The Motley Fool recommends Oneok and recommends the following options: long January 2026 $395 calls on Microsoft and short January 2026 $405 calls on Microsoft. The Motley Fool has a disclosure policy.

BitMine Immersion Technologies (BMNR) has expanded its Ethereum holdings once again, acquiring 23,823 ETH valued at approximately $103.7 million, according to recent on-chain data. The move reinforces BitMine's standing as the largest corporate holder of Ethereum (ETH) globally, outpacing other institutional players.

Wrapped tokens crashed as Binance's infrastructure buckled, making it harder for market makers to stabilize prices. Oct 12, 2025, 5:12 p.m.

Binance has voluntarily announced compensation for users who incurred losses due to platform's disruptions late Friday that triggered a significant price crash in wrapped beacon ether (wBETH), Binance Staked SOL (BNSOL), and Ethereum's synthetic dollar USDe.

"Due to significant market fluctuations over the past 16 hours and a substantial influx of users, some users have encountered issues with their transactions. I deeply apologize for this. If you have incurred losses attributable to Binance, please contact our customer service to register your case," Yi He, co-founder and chief customer officer at Binance, said on X.

STORY CONTINUES BELOW

He added that the exchange will review account activity on a case-by-case basis to determine compensation, emphasizing that losses due to market fluctuations and unrealized profits are not eligible for compensation.

Binance's wrapped beacon ether (wBETH) price plunged to as low as $430 around 21:40 UTC on Friday, representing a staggering 88% discount compared to the ether-tether (ETH/USDT) spot price, which was trading above $3,800 at the same time.

The Binance Staked SOL (BNBSOL) also tanked to $34.90, trading at a massive discount to the spot price of solana. Meanwhile, Ethena's synthetic dollar USDe, which uses the delta neutral cash-and-carry, slipped rapidly to 65 cents around the same time as wBETH and BNBSOL crashed.

Explaining the crashTokens like wBETH and BNBSOL are designed to track the spot price of their underlying assets closely.

Binance valued these wrapped assets based on their spot market prices, as noted by AltLayer founder YQ Jia on X. Under normal conditions, arbitrageurs help maintain these prices close to their fundamental values by simultaneously buying the cheaper asset and selling the more expensive one.

However, as Binance's infrastructure came under stress due to increased market volatility and massive liquidations, market makers and arbitrageurs couldn't access the primary markets and execute trades efficiently, causing a breakdown in price alignment. It led to a crash in wrapped tokens.

"Binance represents perhaps 50% of global spot volume. When they [market makers] can't access Binance—either to hedge positions or even see prices—they're flying blind. Would you provide bids for wBETH at $2,000 when you can't see what's happening on the largest market? Of course not," Jia noted.

Jia added that market makers' inability to participate created a liquidity vacuum, reminiscent of portfolio insurance in 1987 – "mechanisms designed for normal markets that become procyclical accelerants during crashes."

Corrective measuresWithin 24 hours of the crash, Binance announced a shift to using conversion-ratio pricing for wrapped assets.

Instead of valuing wBETH based on volatile and distressed spot market trades, the exchange would now price it according to the underlying staking ratio, which represents the actual amount of ETH each wrapped token represents.

The change means a more stable and accurate valuation during times of market stress by disconnecting wrapped token prices from short-term spot market fluctuations.

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Total Crypto Trading Volume Hits Yearly High of $9.72T

Sep 9, 2025

Combined spot and derivatives trading on centralized exchanges surged 7.58% to $9.72 trillion in August, marking the highest monthly volume of 2025

What to know:

Combined spot and derivatives trading on centralized exchanges surged 7.58% to $9.72 trillion in August, marking the highest monthly volume of 2025Gate exchange emerged as major player with 98.9% volume surge to $746 billion, overtaking Bitget to become fourth-largest platformOpen interest across centralized derivatives exchanges rose 4.92% to $187 billionView Full Report

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Green Shoots on China Lifts Crypto in Sunday Action

34 minutes ago

Both Beijing and Washington moved to calm trade tensions over the weekend.

What to know:

Crypto markets are posting gains Sunday on eased trade tensions betwen D.C. and Beijing.The moves, though, don't come close to erasing the historic declines seen Friday.Read full story

Crypto Sensei said that the last three months of the year have often been positive for crypto. “October, November, and December tend to be bullish months,” he said on Paul Barron Podcast. He expects Bitcoin to reach between $150,000 and $175,000 and Ethereum to rise toward $8,000–$10,000. He added that XRP could also benefit from several strong catalysts building around the project.

Regulatory Clarity Could Help XRPOne major factor is the Clarity Act, which could finally define how U.S. regulators treat digital assets. Sensei said that the bill could be a major turning point once Congress and the Senate reconvene. But he also warned that the process will take time.

 “When the President signs the bill, it doesn’t come into effect right away,” he explained. “Agencies like the SEC and CFTC must write rules, ask for public comments, and make adjustments. That can take years.”

He compared it to the Dodd-Frank Act, which took more than three years to roll out after the 2008 financial crisis. Still, he said that the Clarity Act would mark a clear step forward and could encourage institutions to engage more with XRP and similar tokens.

Ripple’s Partnership With Financial GiantsA new partnership announcement added fuel to XRP’s outlook. Ripple, Securitize, BlackRock, and Vanguard are working together to tokenize money market funds, a sector worth more than $7.4 trillion. The plan will let fund holders redeem assets directly on-chain using Ripple’s RLUSD stablecoin.

The host, Paul Barron called this development a major milestone. “BlackRock, Vanguard, and Ripple in one project shows how traditional finance and crypto are starting to connect,” he said.

BlackRock manages more than $12.5 trillion in assets, but only about $2 billion is currently tied to tokenized funds. Vanguard holds about $74 million on-chain. The numbers show that tokenization is still small, but the entry of such large players could change that.

What It Means for XRPRipple’s role in this shift could help XRP find new demand. The network is already designed for cross-border settlements and on-chain liquidity, making it well-suited for real-world asset tokenization.

Sensei said that this connection between Ripple and financial firms is still being underestimated.
“People don’t yet see how much institutional money could move through Ripple’s network once tokenization grows,” he said.

Trust with CoinPedia:CoinPedia has been delivering accurate and timely cryptocurrency and blockchain updates since 2017. All content is created by our expert panel of analysts and journalists, following strict Editorial Guidelines based on E-E-A-T (Experience, Expertise, Authoritativeness, Trustworthiness). Every article is fact-checked against reputable sources to ensure accuracy, transparency, and reliability. Our review policy guarantees unbiased evaluations when recommending exchanges, platforms, or tools. We strive to provide timely updates about everything crypto & blockchain, right from startups to industry majors.

Investment Disclaimer:All opinions and insights shared represent the author's own views on current market conditions. Please do your own research before making investment decisions. Neither the writer nor the publication assumes responsibility for your financial choices.

Sponsored and Advertisements:Sponsored content and affiliate links may appear on our site. Advertisements are marked clearly, and our editorial content remains entirely independent from our ad partners.

Ethereum (ETH) could be preparing for a major rally, according to Fundstrat Global Advisors Managing Director Mark Newton, who believes the asset's recent weakness will soon give way to a powerful upward move. Newton's analysis suggests that the ongoing correction represents the final stage of a “three-wave pullback,” setting the stage for a potential surge toward $5,500.

The recent crypto market crash stunned investors across the globe, but one analyst saw it coming long before it happened. Bitcoin plunged from above $125,000 to briefly below $102,000, and Ethereum dropped to below $3,800, exactly as predicted by popular market commentator Ash Crypto earlier this month. 

His October 1 post on X warned of a sharp correction meant to liquidate all the bulls before a major rebound in Q4. Now that the dip has played out exactly as he forecasted, Ash Crypto’s outlook for the coming weeks is a powerful rebound phase.

The Crash Prediction That Shook ‘Uptober’
The sell-off that sent shockwaves through the industry is a quick change in sentiment after Bitcoin’s recent all-time high on October 6. Bitcoin’s decline from above $125,000 to below $110,000 caused widespread panic that flowed into other cryptocurrencies, while Ethereum followed with a sharp drop below $3,800. More than $19 billion in leveraged trades were liquidated across different exchanges in under a day, making it one of the largest wipeouts in crypto history.

However, the timing of the crash aligned almost perfectly with a projection on the social media platform X by Ash Crypto. On October 1, Ash Crypto outlined what he called a “pump-then-dump setup” designed to trap overconfident bulls. In his post, he warned that early-month gains would bait retail traders into believing PUMPtober was real before the market reversed violently to shake them out.

Notably, the analyst predicted that Bitcoin would dip to around $106,000 and Ethereum to $3,800 or lower before rebounding later in the month. According to him, this correction phase would run until mid-October, sometime around the 15th to 20th of October, before transitioning into a powerful recovery in the last ten days of the month.

BTCUSD currently trading at $114,049. Chart: TradingView
What Comes Next After The Drop?
Ash Crypto’s call has proven accurate, especially against the backdrop of widespread ‘Uptober’ optimism that clouded judgment for many crypto traders. However, despite the predicted bearish move, the prediction post also carried a long-term sentiment that aligns with a bullish Uptober.

He explained that once market sentiment turns overwhelmingly bearish and traders begin to assume PUMPtober is canceled, short positions will pile up. It is at this point that a reversal will begin in the final ten days of October, leading to what he described as Q4 parabolic candles.

Ash Crypto projected Bitcoin will reach between $150,000 and $180,000 by the end of the fourth quarter, while Ethereum will be trading anywhere in the $8,000 to $12,000 range. Following that move, he expects a full-fledged altcoin season that will cause the price of many altcoins to grow 10x to 50x in just a few months.

At the time of writing, Bitcoin is trading at $114,049, and Ethereum is trading at $4,087.

Featured image from Unsplash, chart from TradingView

Bitcoin Cash (BCH) is a cryptocurrency that was created in August 2017 as a result of a hard fork from the original Bitcoin (BTC) blockchain.

Bitcoin Cash is a separate cryptocurrency from Bitcoin (BTC) that works with its own blockchain. While it shares similarities with Bitcoin, including its decentralized nature and limited supply, the differences in block size and development philosophy make them distinct entities.

It was created when a group of developers and miners initiated the fork to address some of the perceived limitations of the original Bitcoin network.

What makes BCH different

One of the main differences between Bitcoin Cash and Bitcoin is the block size. Bitcoin's block size is limited to 1 MB, which can lead to slower transaction processing times during times of high demand. In contrast, Bitcoin Cash's block size was initially increased to 8 MB (later to 32 MB) to accommodate more transactions and increase the throughput of the network.

The larger block size allows Bitcoin Cash to process more transactions per block, resulting in faster transaction confirmation times and, in many cases, lower transaction fees compared to BTC.

Bitcoin Cash aims to solve the scalability problem that Bitcoin has with the increasing number of users and transactions.

Similar to Bitcoin, Bitcoin Cash has a decentralized development community that is continuously working on protocol upgrades and improvements.

Community acceptance and widespread adoption

Bitcoin Cash has gained a dedicated community of users and advocates who are committed to its adoption as a peer-to-peer electronic cash system.

Bitcoin Cash is accepted by various merchants and businesses and can be traded on numerous cryptocurrency exchanges.

Disclaimer. This article is for informational purposes only and should not be viewed as an endorsement by Coinidol.com. The data provided is collected by the author and is not sponsored by any company or token developer. They are not a recommendation to buy or sell cryptocurrency. Readers should do their research before investing in funds.

BNB has staged a sharp recovery after a volatile week that saw most major cryptocurrencies fall. The token rose more than 11% in the last 24 hours, trading near $1,267 at press time.

Market Rebounds After Tariff ShockA surprise announcement of 100% U.S. tariffs on Chinese imports caused a short-term market crash, sending prices of major digital assets lower. However, BNB has bounced back faster than most, showing strength compared to other large-cap coins.

$BNB is insanely strong, this surprised me a bit seeing the move today. All majors are bouncing a bit but BNB outperformance still confirms that BSC/BNB ecosystem is the place to play for now. pic.twitter.com/cYDbjJerKo

— Altcoin Sherpa (@AltcoinSherpa) October 12, 2025 Analysts said the move shows the continued resilience of the BNB Chain (BSC) ecosystem, which remains active in development and user activity despite broader market stress.

CZ Addresses BNB’s Price StrengthBinance founder Changpeng Zhao (CZ) commented on BNB’s recent performance on social media. He said that unlike many other projects, BNB has no market makers influencing its price.

“Many projects have a market maker. BNB doesn’t. I am not aware of any of my affiliated entities buying or selling BNB in the past days or weeks,” CZ wrote. 

He added that BNB’s value comes from its builders, community, and deflationary token model, not coordinated trading or artificial support. BNB regularly burns tokens, reducing supply over time.

Technical Picture: Signs of a Short-Term ReversalBNB dropped to as low as $863 during the market liquidation but quickly recovered above $1,200. On the 4-hour chart, the token has now broken above the EMA10 and MA20 levels, showing a possible short-term trend reversal.

If the price holds above $1,200, the next resistance zone sits between $1,300 and $1,360. Analysts say that staying stable above key moving averages will confirm stronger recovery momentum.

Trust with CoinPedia:CoinPedia has been delivering accurate and timely cryptocurrency and blockchain updates since 2017. All content is created by our expert panel of analysts and journalists, following strict Editorial Guidelines based on E-E-A-T (Experience, Expertise, Authoritativeness, Trustworthiness). Every article is fact-checked against reputable sources to ensure accuracy, transparency, and reliability. Our review policy guarantees unbiased evaluations when recommending exchanges, platforms, or tools. We strive to provide timely updates about everything crypto & blockchain, right from startups to industry majors.

Investment Disclaimer:All opinions and insights shared represent the author's own views on current market conditions. Please do your own research before making investment decisions. Neither the writer nor the publication assumes responsibility for your financial choices.

Sponsored and Advertisements:Sponsored content and affiliate links may appear on our site. Advertisements are marked clearly, and our editorial content remains entirely independent from our ad partners.

Following a brief market-wide dip on October 10, BNB swiftly rebounded, emerging as the only high-cap altcoin to fully recover. While the rally has attributed to the growing appeal of the BNB Chain, experts emphasized that the chain's long-term relevance will hinge on its ability to strengthen and evolve its underlying “trust architecture.

Coinbase is preparing to launch a new American Express credit card in the U.S. this fall, with design and rewards specifically tailored for Bitcoin enthusiasts.

Summary

Coinbase is teaming up with American Express to launch a Bitcoin-themed credit card in the U.S. this fall — a move that blends crypto culture with traditional finance.
Unlike standard crypto cards that emphasize cashback or token rewards, this one is designed to celebrate Bitcoin’s origins and decentralized ethos, signaling Coinbase’s intent to cater directly to Bitcoin purists.
The timing aligns with a surge in institutional adoption and mainstream interest in BTC, positioning the card as both a lifestyle statement and a strategic play for deeper engagement with the Bitcoin community.

Design elements show Bitcoin heritage
According to CoinDesk, the card distinguishes itself from typical crypto-linked products by centering on Bitcoin’s origin story and symbolism rather than just offering standard perks.

Details about specific reward structures and card benefits are expected to be announced closer to the fall launch date.

Unlike most crypto-linked cards that focus primarily on cashback or rewards mechanics, Coinbase’s upcoming American Express product emphasizes Bitcoin’s cultural significance and founding principles.

The design approach suggests the card will incorporate visual or conceptual elements that resonate with Bitcoin’s decentralized ethos and monetary philosophy.

The choice to partner with American Express rather than Visa or Mastercard provides access to Amex’s premium merchant network and customer base.

Coinbase’s existing card products have offered cryptocurrency rewards on purchases. However, this new Bitcoin-focused American Express card appears to be designed to deepen engagement specifically within the Bitcoin community.

Strategic timing as Bitcoin adoption grows
The fall 2025 launch timing coincides with growing institutional Bitcoin (BTC) adoption through spot ETFs and increasing mainstream acceptance of cryptocurrency payments.

The product could appeal to Bitcoin maximalists who prefer Bitcoin-specific offerings over multi-cryptocurrency products.

By tailoring the card explicitly for Bitcoin users, Coinbase acknowledges the distinct identity and preferences of the Bitcoin community compared to other cryptocurrency holders.

XRP traded at $2.49 on Oct. 12, 2025, at 11:50 a.m., with a market capitalization of $148.7 billion and a 24-hour trading volume of $8.49 billion. The cryptocurrency moved within an intraday range of $2.32 to $2.52, while the weekly range extended from $2.32 to $3.05.

Cover image via U.Today

Disclaimer: The opinions expressed by our writers are their own and do not represent the views of U.Today. The financial and market information provided on U.Today is intended for informational purposes only. U.Today is not liable for any financial losses incurred while trading cryptocurrencies. Conduct your own research by contacting financial experts before making any investment decisions. We believe that all content is accurate as of the date of publication, but certain offers mentioned may no longer be available.

The crypto market cratered over the weekend, with Bitcoin setting a number of firsts.

The sell-off began Friday as investors reacted to macroeconomic concerns, with Bitcoin sharply plunging from a high of $122,600 to reach $107,000.

The drop continued on Saturday with Bitcoin marking three straight days of declines since Oct. 6.

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Amid the sell-off on Saturday, crypto's total market cap fell to $3.76 trillion with $19.36 billion liquidated across digital assets, according to CoinGlass data, marking the biggest crypto liquidation event ever.

At the time of writing, total crypto market capitalization was lower, currently at $3.72 trillion, as most crypto assets still traded down on daily and weekly basis.

Bitcoin still remains in red, down 0.25% in the last 24 hours and down 11% weekly.

Bitcoin sets recordBitcoin has set new records amid the market sell-off, albeit not in price. As Bitcoin fell from $122,600 on Friday to about $107,000, it printed its first-ever $20,000 daily candle; however, not the green one usually expected, it was a red candle, highlighting its crash.

Likewise, a new record was set in the futures market, also a not-so-pleasant one, with the biggest open interest wipeout. According to Glassnode, Bitcoin futures markets experienced their largest single-day open interest wipeout in history, with over $11 billion in positions cleared. This highlights massive deleveraging in the market, with a substantial number of traders recording losses.

The next major support level for Bitcoin is $100,000, a close below which would signal the end of the past three-year bull cycle. Bitcoin options market reflected this with the highest number of "put" or sell strikes at $110,000 and the next highest at $100,000, according to data on the Deribit platform.

Sun, 12/10/2025 - 16:33

David Schwartz, one of XRPL architects, shares a memory of the internet

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Disclaimer: The opinions expressed by our writers are their own and do not represent the views of U.Today. The financial and market information provided on U.Today is intended for informational purposes only. U.Today is not liable for any financial losses incurred while trading cryptocurrencies. Conduct your own research by contacting financial experts before making any investment decisions. We believe that all content is accurate as of the date of publication, but certain offers mentioned may no longer be available.

Ripple CTO David Schwartz recently participated in an X discussion, which wasn't based on cryptocurrencies per se, but a topic with a likely inclination: the internet.

Schools of thought refer to Web3 as the next iteration of the internet, albeit decentralized, with blockchain being the key technology behind it.

The discussion began when Nikita Bier, the head of product at X and advisor at Solana, threw a question at his 616,600 X followers, asking them what their earliest memory of the internet was.

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The tweet caught the attention of the Ripple CTO, who shared his earliest memory of the internet to be "editing DOS startup files to load a packet driver, configuring SLIP on SLS Linux (on 14 floppy disks), and memorizing bang paths."

Editing DOS startup files to load a packet driver, configuring SLIP on SLS Linux (on 14 floppy disks), and memorizing bang paths. https://t.co/0bnQEgWvRO

— David 'JoelKatz' Schwartz (@JoelKatz) October 12, 2025 This knowledge of the internet was what the Ripple CTO built on, going on to create XRP in 2012, although work on XRP Ledger began in 2011.

In June 2012, David Schwartz, Jed McCaleb and Arthur Britto launched a distributed ledger that improved upon these fundamental limitations of Bitcoin, XRP Ledger, with its native cryptocurrency XRP.

Internet of valueCryptocurrency and blockchain are transforming the exchange of value, much as the internet did for the exchange of information, and the journey is expected to be very much the same. The cryptocurrency movement emerged from the ashes of the 2008 financial crisis with the belief that the financial system could be improved to benefit everyone.

Cryptocurrency’s use cases vary worldwide, with more use cases possible with emerging Web3 technologies.

In this light, XRP Ledger's updated institutional DeFi road map prepares for what lies ahead in the next months. This focuses on two themes shaping the next stage of XRPL’s institutional DeFi evolution: the launch of a native lending protocol and the integration of zero-knowledge proofs (ZKPs) for privacy with accountability.

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Nearly all participants (11 of 12) experienced clinically meaningful hearing improvements, including three who achieved normal hearing; eight with longer follow-up showed stability or continued improvement in their hearing

Among three who completed speech assessments, all showed significant improvement with one able to identify one- and two-syllable words with no visual cues and respond to distant sounds and speech in noisy environments

Latest DB-OTO data presented at AAO-HNSF; U.S. regulatory submission planned later this year, pending discussions with the FDA

TARRYTOWN, N.Y., Oct. 12, 2025 (GLOBE NEWSWIRE) -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced updated data for their investigational gene therapy DB-OTO for profound genetic hearing loss due to variants of the otoferlin (OTOF) gene were published in The New England Journal of Medicine and presented during an oral presentation at the annual American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNSF) meeting. These latest results from the pivotal CHORD trial show 11 out of 12 participants have experienced clinically meaningful hearing improvements, including 3 who achieved normal hearing levels. Additionally, eight participants with longer follow-up showed stability or continued improvement in their hearing, and among three who completed speech assessments, all showed significant improvement.

“Until now, genetic OTOF-related hearing loss was considered permanent, which is why many of us have dedicated our careers to this field,” said Lawrence R. Lustig, M.D., Chair of the Department of Otolaryngology-Head and Neck Surgery at the Columbia University College of Physicians and Surgeons and a trial investigator. “This registrational data set showcases consistent, rapid and robust responses to DB-OTO, and for those followed to later timepoints, we’ve seen hearing stability as well as continued improvement in understanding of speech. These results are even more poignant when viewed by the families – as one of the parents said, their situation is now ‘unimaginable’ from one year ago. This truly represents a new era in the treatment of hearing loss.”

The CHORD trial evaluated pediatric participants with profound hearing loss due to variants of the OTOF gene that received a single administration of DB-OTO via intracochlear infusion. Among 12 participants (aged 10 months to 16 years), nine received the gene therapy unilaterally (in one ear) and three received it bilaterally (in both ears). The surgical procedure to administer DB-OTO leverages an approach similar to cochlear implantation, which enables use in young infants.

Nearly all participants (11 of 12; 14 of 15 treated ears) demonstrated improved hearing, responding within weeks of treatment. As published and presented, the trial met the primary endpoint with 9 participants experiencing hearing improvements at a threshold of ≤70 decibel hearing level (dBHL) as assessed by behavioral pure tone audiometry (PTA) at week 24. This threshold corresponds to a clinical standard that typically does not require cochlear implantation and enables natural acoustic hearing. Notably, 6 could hear soft speech without assistive devices, and 3 were further able to detect whispers (achieving normal hearing sensitivity). One participant who did not meet the primary PTA endpoint at week 24 further improved to achieve “nearly normal” hearing sensitivity at week 48. Nine participants also demonstrated an auditory brainstem response (ABR) at ≤90 decibels (dB), achieving the trial’s key secondary endpoint.

Hearing improvements remained stable or continued to improve in 8 participants who had follow-up visits of ≥36 weeks (up to 72 weeks). Speech development was also assessed in the 3 participants who were followed at least 48 weeks and all showed significant improvements. One of these participants demonstrated the ability to identify one- and two-syllable words with no visual cues and could respond to distant sounds and speech in noisy environments.

Across all 12 participants, both the surgical procedure and DB-OTO were well tolerated, and there were no DB-OTO-related adverse findings reported. Two participants experienced serious adverse events: one was attributed to a cochlear implant surgical complication and the other to a recent vaccination. Some participants experienced transient post-surgical vestibular adverse events (e.g., nystagmus, nausea, dizziness, vomiting), all of which fully resolved.

The U.S. regulatory application for DB-OTO is planned for later this year, pending discussions with the U.S. Food and Drug Administration (FDA). DB-OTO received Orphan Drug, Rare Pediatric Disease, Fast Track and Regenerative Medicine Advanced Therapy designations from the FDA. The European Medicines Agency also granted Orphan Drug Designation.

The potential use of DB-OTO for OTOF-related hearing loss is currently under clinical investigation, and its safety and efficacy have not been evaluated by any regulatory authority.

About OTOF-related Hearing Loss
Permanent congenital hearing loss (present at birth) is a significant unmet medical need that affects approximately 1.7 out of every 1,000 children born in the U.S. and approximately half of these cases have genetic causes. Notably, otoferlin-related hearing loss is ultra-rare, affecting 20-50 newborns per year in the U.S. This specific condition is caused by variants in the OTOF gene, which lead to a lack of a functional otoferlin protein that is critical for the communication between the sensory cells of the inner ear and the auditory nerve.

About the CHORD Trial
The CHORD trial is a registrational Phase 1/2 multicenter, open-label trial to evaluate the safety, tolerability and efficacy of DB-OTO in infants, children and adolescents with OTOF-related hearing loss. The trial is currently enrolling children (<18 years of age) across sites in the U.S., United Kingdom, Spain and Germany.

CHORD is being conducted in two parts. In the initial dose-escalation cohort (Part A), participants receive a single intracochlear infusion of DB-OTO in one ear. In the expansion cohort (Part B), participants receive DB-OTO in both ears at the selected dose from Part A.

Hearing improvements were assessed by PTA and ABR. PTA is the gold standard measurement of hearing sensitivity and is measured through behavioral responses to sound (e.g., turning head towards sound) that is emitted at different intensity levels and measured in dB. ABR corroborates these behavioral responses, serving as an objective confirmation of hearing function, and is measured through recording electrical brainstem responses to sound emitted at different intensity levels measured in dBs. At baseline, all participants had profound hearing loss (behavioral PTA), and no electrophysiological (ABR) responses at maximum sound levels.

Additional information about the trial, including enrollment, can be obtained by contacting [email protected].

About DB-OTO and the Regeneron Auditory Program
DB-OTO is an investigational cell-selective, dual adeno-associated virus (AAV) vector gene therapy designed to provide durable, physiological hearing to individuals with profound, congenital hearing loss caused by variants of the OTOF gene. The treatment aims to deliver a working copy of the OTOF gene to replace the non-functional otoferlin protein using a modified, non-pathogenic virus that is delivered via an infusion into the cochlea under general anesthesia (similar to the procedure used for cochlear implantation). In this gene therapy, the newly introduced OTOF gene is under the control of a proprietary cell-specific Myo15 promoter, which is intended to restrict expression only to hair cells that normally express otoferlin.

In addition to OTOF, Regeneron is committed to investigating several other targets for genetic forms of hearing loss.

About Regeneron
Regeneron (NASDAQ: REGN) is a leading biotechnology company that invents, develops and commercializes life-transforming medicines for people with serious diseases. Founded and led by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to numerous approved treatments and product candidates in development, most of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurological diseases, hematologic conditions, infectious diseases, and rare diseases.

Regeneron pushes the boundaries of scientific discovery and accelerates drug development using our proprietary technologies, such as VelociSuite®, which produces optimized fully human antibodies and new classes of bispecific antibodies. We are shaping the next frontier of medicine with data-powered insights from the Regeneron Genetics Center® and pioneering genetic medicine platforms, enabling us to identify innovative targets and complementary approaches to potentially treat or cure diseases.

For more information, please visit, www.Regeneron.com or follow Regeneron on LinkedIn, Instagram, Facebook or X.

Forward-Looking Statements and Use of Digital Media
This press release includes forward-looking statements that involve risks and uncertainties relating to future events and the future performance of Regeneron Pharmaceuticals, Inc. (“Regeneron” or the “Company”), and actual events or results may differ materially from these forward-looking statements. Words such as “anticipate,” “expect,” “intend,” “plan,” “believe,” “seek,” “estimate,” variations of such words, and similar expressions are intended to identify such forward-looking statements, although not all forward-looking statements contain these identifying words. These statements concern, and these risks and uncertainties include, among others, the nature, timing, and possible success and therapeutic applications of products marketed or otherwise commercialized by Regeneron and/or its collaborators or licensees (collectively, “Regeneron’s Products”) and product candidates being developed by Regeneron and/or its collaborators or licensees (collectively, “Regeneron’s Product Candidates”) and research and clinical programs now underway or planned, including without limitation the investigational gene therapy DB-OTO; the likelihood, timing, and scope of possible regulatory approval and commercial launch of Regeneron’s Product Candidates and new indications for Regeneron’s Products, such as DB-OTO for the treatment of otoferlin-related hearing loss; uncertainty of the utilization, market acceptance, and commercial success of Regeneron’s Products and Regeneron’s Product Candidates and the impact of studies (whether conducted by Regeneron or others and whether mandated or voluntary), including the studies discussed or referenced in this press release, on any of the foregoing or any potential regulatory approval of Regeneron’s Products and Regeneron’s Product Candidates (such as DB-OTO); the ability of Regeneron’s collaborators, licensees, suppliers, or other third parties (as applicable) to perform manufacturing, filling, finishing, packaging, labeling, distribution, and other steps related to Regeneron’s Products and Regeneron’s Product Candidates; the ability of Regeneron to manage supply chains for multiple products and product candidates and risks associated with tariffs and other trade restrictions; safety issues resulting from the administration of Regeneron’s Products and Regeneron’s Product Candidates (such as DB-OTO) in patients, including serious complications or side effects in connection with the use of Regeneron’s Products and Regeneron’s Product Candidates in clinical trials; determinations by regulatory and administrative governmental authorities which may delay or restrict Regeneron’s ability to continue to develop or commercialize Regeneron’s Products and Regeneron’s Product Candidates; ongoing regulatory obligations and oversight impacting Regeneron’s Products, research and clinical programs, and business, including those relating to patient privacy; the availability and extent of reimbursement or copay assistance for Regeneron’s Products from third-party payors and other third parties, including private payor healthcare and insurance programs, health maintenance organizations, pharmacy benefit management companies, and government programs such as Medicare and Medicaid; coverage and reimbursement determinations by such payors and other third parties and new policies and procedures adopted by such payors and other third parties; changes in laws, regulations, and policies affecting the healthcare industry; competing drugs and product candidates that may be superior to, or more cost effective than, Regeneron’s Products and Regeneron’s Product Candidates (including biosimilar versions of Regeneron’s Products); the extent to which the results from the research and development programs conducted by Regeneron and/or its collaborators or licensees may be replicated in other studies and/or lead to advancement of product candidates to clinical trials, therapeutic applications, or regulatory approval; unanticipated expenses; the costs of developing, producing, and selling products; the ability of Regeneron to meet any of its financial projections or guidance and changes to the assumptions underlying those projections or guidance; the potential for any license, collaboration, or supply agreement, including Regeneron’s agreements with Sanofi and Bayer (or their respective affiliated companies, as applicable), to be cancelled or terminated; the impact of public health outbreaks, epidemics, or pandemics on Regeneron's business; and risks associated with litigation and other proceedings and government investigations relating to the Company and/or its operations (including the pending civil proceedings initiated or joined by the U.S. Department of Justice and the U.S. Attorney's Office for the District of Massachusetts), risks associated with intellectual property of other parties and pending or future litigation relating thereto (including without limitation the patent litigation and other related proceedings relating to EYLEA® (aflibercept) Injection), the ultimate outcome of any such proceedings and investigations, and the impact any of the foregoing may have on Regeneron’s business, prospects, operating results, and financial condition. A more complete description of these and other material risks can be found in Regeneron’s filings with the U.S. Securities and Exchange Commission, including its Form 10-K for the year ended December 31, 2024 and its Form 10-Q for the quarterly period ended June 30, 2025. Any forward-looking statements are made based on management’s current beliefs and judgment, and the reader is cautioned not to rely on any forward-looking statements made by Regeneron. Regeneron does not undertake any obligation to update (publicly or otherwise) any forward-looking statement, including without limitation any financial projection or guidance, whether as a result of new information, future events, or otherwise.

Regeneron uses its media and investor relations website and social media outlets to publish important information about the Company, including information that may be deemed material to investors. Financial and other information about Regeneron is routinely posted and is accessible on Regeneron's media and investor relations website (https://investor.regeneron.com) and its LinkedIn page (https://www.linkedin.com/company/regeneron-pharmaceuticals).