Market Signal Briefing

TL;DR

Trader “Machi Big Brother” holds a 25x leveraged long position on ETH valued at $10.1 million.
With ETH dropping below $3,900, his position faces Ethereum liquidation risk if the price falls to $3,803.
The trader is using 95.72% of his margin, with over $404,000 at immediate risk of being liquidated.

The well-known investor and “whale” Jeffrey Huang, alias “Machi Big Brother,” doubled his bullish bet on Ethereum, putting him in a precarious position. This comes just as the market shows signs of weakness. ETH is trading lower, down 4% in the last 24 hours, threatening Huang’s entire margin.

Despite the market downturn, Huang has continued to increase his exposure. Over the weekend, he received 220,000 USDC from the investment firm QCP Capital and deposited it into the derivatives platform Hyperliquid to add to his long position.

Although ETH had a brief rally to $4,077 at the start of the week, it was quickly rejected, falling below $3,900. Ignoring the drop, Huang deposited an additional $100,000 USDC today, raising his total position to 2,575 ETH, valued at approximately $10.14 million.

Margin Depletes as Liquidation Looms at $3,800
Analysis of Huang’s position reveals the extreme danger of his bet. According to data from Hyperdash, the trade is 25x leveraged, with an average entry price of $3,955.13.

With ETH’s current price hovering around $3,894, the position is already significantly “underwater,” with an unrealized loss of over $164,000. The Ethereum liquidation risk is imminent: Huang’s liquidation threshold now sits at $3,803.86.

Critically, his margin usage has reached 95.72%. This means he has over $404,000 in collateral at immediate risk, with almost no room to absorb further downside volatility. If ETH falls below $3,803, he will lose his entire deposited margin, unless he adds more USDC as collateral.

This risky strategy is not new for Huang, who lost $35 million in profits during “Uptober” on a similar bet on the XPL token. Meanwhile, the ETH market remains under bearish pressure after failing at the $4,080 resistance, keeping the price in a tight range that jeopardizes overleveraged positions.

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Ripple’s longtime chief technologist David “JoelKatz” Schwartz has unveiled his first post-Ripple move, saying he will serve as a strategic advisor to Evernorth, an XRP-focused vehicle led by former Ripple executive Asheesh Birla. “XRP community – I promised I’d have an update on my next adventure soon right? Well here’s the start: I’ll be a strategic advisor to Evernorth, helmed by my friend Asheesh Birla,” Schwartz wrote, adding that Evernorth was founded “as a regulated, scalable investment vehicle to tap into opportunities for XRP in DeFi and capital markets, extending the entire XRP ecosystem.” He closed with: “I’m excited to get started!”

The Old Ripple Connection
Schwartz’s announcement arrived alongside Evernorth’s own reveal that it has signed a business combination agreement with Armada Acquisition Corp II to go public on Nasdaq. The combined company is “expected to trade on Nasdaq under the ticker symbol ‘XRPN,’ subject to the satisfaction of the listing requirements,” with more than $1 billion in gross proceeds targeted, including a $200 million commitment from Japan’s SBI. The release says net proceeds will primarily fund open-market XRP purchases, positioning Evernorth as “the largest public XRP treasury company.”

The Birla–Schwartz connection is longstanding. Birla joined Ripple in 2013 and rose to become General Manager of RippleNet, the company’s cross-border payments business, before moving to the company’s board in 2022. On the day he stepped back from his “day job”, Birla wrote: “After ~9 amazing years I’ve decided to wrap up my day job at Ripple. Luckily, I’m not going far as I join the Board of Directors.” In announcing Evernorth this week, Birla said he will step down from Ripple’s board to lead the new venture.

Schwartz’s advisory role at Evernorth intersects with his own transition out of Ripple’s C-suite. Earlier this month, he disclosed that he will step down as Ripple’s Chief Technology Officer at year-end after more than a decade in the role, moving to Ripple’s board and remaining active in the XRP Ledger community. He revealed that he wants to spend more time with family while “not going away from the XRP community.”

Evernorth’s capital-markets blueprint is expansive. The company plans to use its war chest to accumulate XRP and to “actively grow XRP per share over time” by lending to institutions, providing market liquidity and deploying capital into XRP-based DeFi strategies.

The press release outlines complementary ecosystem initiatives—running XRPL validators, using Ripple’s RLUSD stablecoin as an on-ramp to XRP DeFi, and supporting projects across payments, capital markets and tokenized assets—framing Evernorth as both a treasury vehicle and a development catalyst. The company says Ripple will participate as a strategic investor, and that Ripple executives Brad Garlinghouse, Stuart Alderoty and David Schwartz are expected to serve as strategic advisors while Evernorth maintains independent governance.

For XRP’s institutional storyline, the architecture matters. By targeting an exchange listing under “XRPN” and explicitly eschewing a passive ETF wrapper, Evernorth positions itself as an active, yield-generating public company with a balance sheet anchored in XRP. If the deal secures shareholder and regulatory approvals, the parties are aiming to close in the first quarter of 2026, converting non-redeemed AACI Class A shares one-for-one into Evernorth shares at closing.

Schwartz’s phrasing—“here’s the start”—reads like a deliberate tell that his Evernorth role is only the first of multiple XRP-aligned ventures he plans to take on following his CTO transition. He has already confirmed he will remain engaged with XRPL and Ripple at the board level; today’s advisory post adds a capital-markets dimension to that presence.

At press time, XRP traded at $2.42.

XRP price, 1-day chart | Source: XRPUSDT on TradingView.com
Featured image from YouTube, chart from TradingView.com

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Jake Simmons has been a Bitcoin enthusiast since 2016. Ever since he heard about Bitcoin, he has been studying the topic every day and trying to share his knowledge with others. His goal is to contribute to Bitcoin's financial revolution, which will replace the fiat money system. Besides BTC and crypto, Jake studied Business Informatics at a university. After graduation in 2017, he has been working in the blockchain and crypto sector. You can follow Jake on Twitter at @realJakeSimmons.

BNB Falls 3.3% as Market Shakeout Cuts Through SupportThe sell-off was fueled by heavy selling pressure, with trading volume surging 87% and algorithmic trading triggering a cascade of sell orders Oct 21, 2025, 12:03 p.m.

BNB, the native token of the BNB Chain that’s also used for discounts on Binance fees, dropped 3.3% in the past 24 hours, falling from $1,117 to as low as $1,063 before stabilizing just below $1,080.

The sell-off erased recent gains and cut through key technical levels, according to CoinDesk Research's technical analysis data model. Trading volume surged 87% above its 24-hour average during the decline.

The price action followed a sharp drop in bitcoin BTC$108,222.79 and other cryptocurrencies and reflected a wider retreat in crypto markets as the market flushed off excess leverage. The wider market, as measured via the CoinDesk 20 (CD20) index, is down 2.74%.

The downturn gained momentum as algorithmic trading systems kicked in, triggering a cascade of sell orders that pushed prices lower. When demand finally caught up, BNB found tentative support around the $1,070 mark.

Attempts to bounce back were weak. Price stalled near $1,075, where selling resumed, keeping BNB locked in a narrow range. On shorter-term charts, momentum indicators have eased but not reversed, and buyers remain hesitant to commit without a clearer trend.

Whether this level holds could determine if the move was a one-off capitulation or the start of a deeper correction. For now, traders are watching $1,070 as a key support level.

Disclaimer: Parts of this article were generated with the assistance from AI tools and reviewed by our editorial team to ensure accuracy and adherence to our standards. For more information, see CoinDesk's full AI Policy.

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Crypto Markets Today: Bitcoin, Ether Drop as Selling Pressure Returns

Bitcoin and Ethereum fell sharply Tuesday, erasing weekend gains as traders assessed whether the market’s bounce formed a lower high.

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Bitcoin dropped to $107,800 and Ether to $3,867, reversing recent recoveries and approaching levels that could test October lows near $103,700.Futures open interest rose to $26 billion, while funding rates turned neutral to positive. Options data show traders paying a steep premium for upside exposure, signaling expectations of increased volatility.Despite Upbit and Bithumb listings driving temporary spikes in smaller tokens like SynFutures (F) and ZORA, most altcoins faced steep declines, with CAKE and ETHFI sliding about 10%.Read full story

SpaceX has transferred 2,485 BTC (≈$268.5 million) to two new wallet addresses after three months of inactivity.

Bitcoin has swung wildly in recent weeks, with volatility returning this month following a quiet summer and traders suddenly braced for a 2026 bitcoin price shock.

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The bitcoin price has dropped around 15% since hitting an all-time high of $126,000 despite Tesla and SpaceX billionaire Elon Musk breaking his silence on bitcoin.

Now, as analysts warn of an “imminent dollar and financial crisis," Elon Musk’s rocket company SpaceX has moved almost $270 million worth of bitcoin, setting alarm bells ringing as crypto watchers ask if he’s "planning to sell."

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Forbes‘It’s Game Over’—‘Imminent’ Fed U.S. Dollar ‘Crisis’ Predicted To Spark Bitcoin Price Tipping Point As Gold Soars

Elon Musk, cofounder of Tesla and SpaceX, is closely watched by bitcoin and crypto traders due to his ability to move the bitcoin price and crypto markets.

Getty Images

“SpaceX is moving bitcoin to new wallets, are they planning to sell,” investor and commentator Mario Nawfal asked on X.

SpaceX moved almost 2,500 bitcoin to several wallet addresses that remain unmarked on the platform, according to data from Arkham Intelligence, with the platform also showing this was the first change to SpaceX’s total bitcoin holdings since June 2022 when it is believed to have reduced its bitcoin holdings by around 70%.

SpaceX is thought to hold just over 8,000 bitcoin worth around $900 million, while Tesla holds just over 10,000, worth $1.2 billion.

In 2022, Musk sold most of the bitcoin his electric car company Tesla had bought just over a year earlier, causing the bitcoin price to briefly plummet and sending shockwaves through the crypto market.

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ForbesStark Fed ‘Shock’ Warning Issued As Bitcoin Braces For A $6.6 Trillion Price FlipBy Billy Bambrough

The bitcoin price has dropped back from its all-time high of around $126,000 per bitcoin.

Forbes Digital Assets

Last week, Musk, who has said his new political party would support bitcoin over the U.S. dollar, praised bitcoin for being "based on energy" and agreed the bitcoin price has soared amid dollar "debasement" designed "to fund the AI arms race."

"AI is the new global arms race, and capex will eventually be funded by governments (U.S. and China). If you want to know why gold/silver/bitcoin is soaring, it’s the 'debasement’ to fund the AI arms race," the ZeroHedge X account posted, adding: “But you can't print energy.”

Musk responded, saying: “True," and adding: "That is why bitcoin is based on energy: you can issue fake fiat currency, and every government in history has done so, but it is impossible to fake energy.”

Proposed by Anza, a developer of Solana's dominant node software client Agave, the SIMD-0266: Efficient Token Program update is set to bring radical improvement to token operations on Solana (SOL) blockchains. Compared to existing SPL architecture, it might reduce resource usage by 200x.

98% less resource usage: Meet SIMD-0266: Efficient Token Program upgradeSIMD-0266: Efficient Token Program, one of the most crucial Solana improvement proposals of 2025, is expected to be a breakthrough in the efficiency of token creation on Solana (SOL). As explained by Anza, Solana's infrastructure company and proposal author, the compute resources economy might reach 98%.

1/ SIMD-0266: Efficient Token Program, authored by @0x_febo, propose replacing the current SPL token program with a new compute optimized version called p-token. The upgrade will reduce Token program CU usage by up to 98%. Here’s how it works 🧵 pic.twitter.com/5ASETDEYqu

— Anza (@anza_xyz) October 20, 2025 Currently, 10% of block compute units are spent on token program instructions. Designed to replace the SPL standard, p-token will free nearly 12% of block space for other transactions, which, in turn, will enlarge Solana's effective transaction throughput.

Namely, new types of instructions will be added to handle more complex DeFi structures, saving the blockchain compute unit spending:

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New instructions like Batch and UnwrapLamports further reduce compute for common DeFi patterns, allowing multiple token ops per CPI and removing the need for temporary native accounts. Programs can now execute complex flows far more efficiently.

Equipped with 100% backward compatibility, p-token introduction will be a drop-in upgrade: no changes will be expected for existing SPL tokens.

This, in turn, will pave the way for bigger resource allocations for new blocks, with a faster and better performing Solana (SOL) as the endgame goal.

Solana (SOL) up for crucial Alpenglow upgrade in early 2026Solana (SOL) community enthusiasts are welcoming the new design, highlighting that it will unlock previously unseen opportunities for decentralized finance here.

As covered by U.Today previously, Solana (SOL) is incing closer to its Alpenglow upgrade. Slated for early 2026, it is set to retire proof of history and replace it with a more efficient consensus scheme.

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Blockchain Is Breaking Orbit: The Rise of Decentralized Space (Photo by SpaceX via Getty Images)

Getty Images

From Bitcoin’s first space transaction to tokenized lunar domains, blockchain is powering a new decentralized space race that makes access and ownership universal.

When I was a kid, I wanted to be an astronaut. I dreamed about floating in zero gravity, watching Earth spin beneath me, and maybe one day walking on the moon. While I never made it to space, life came full circle later while at AWS, when I worked with a partner who helped Rover get to Mars.

That experience reminded me that there are many ways to explore new frontiers, and today, one of the most exciting isn’t through rockets but through code. Blockchain, the technology that started with digital money, is now expanding into orbit.

Space has always captured human imagination. For decades, it was the realm of governments, billionaires, and aerospace giants.

Now a quiet revolution is bringing it within reach of everyone. Blockchain is moving beyond finance and into orbit, building a foundation for a decentralized space economy.

What Is Decentralized Space? Decentralized space is the merging of blockchain with space exploration. It uses smart contracts, tokenization, and decentralized governance to open participation in the space economy to anyone with a digital wallet.

Instead of relying on a few large institutions, decentralized space allows communities, creators, and investors to co-own and co-govern assets such as satellites, payloads, or even lunar missions. It brings transparency and inclusivity to a domain that has long been exclusive, creating an open network where access and ownership extend beyond Earth.

It merges space technology with Web3 principles of transparency, inclusivity, and verifiable ownership which creates an open network where anyone can contribute to humanity’s journey beyond Earth.

According to PWC, Space will be the first new trillion-dollar asset class of the 21st century and the first that can exist natively on-chain.

Why Is Decentralized Space Linked to Bitcoin?The roots of decentralized space trace back to Bitcoin. In 2019, SpaceChain launched its blockchain node into orbit aboard a SpaceX Falcon 9 rocket. That node enabled Bitcoin multi-signature transactions from space, marking the first-ever blockchain and Bitcoin transaction in orbit. Bitcoin just recently hit an All Time High and then went down again, much like rocketships do!

The roots of decentralized space goes back to bitcoin. (Photo illustration by Dan Kitwood/Getty Images)

Getty Images

That milestone proved that blockchain could function off-planet and be independent of terrestrial infrastructure. It inspired a wave of projects exploring how digital assets and decentralized systems could support future space missions.

What began with Bitcoin has now expanded into a full ecosystem, where tokens, domains, and smart contracts connect people to space in ways never before possible.

Three pioneering projects are leading this transformation

SpaceCoin is creating a blockchain infrastructure that works through satellites.Copernic Space is tokenizing space assets and digital domains linked to lunar missions.The Open Network, or TON, the blockchain behind Telegram, is enabling on-chain voting for real astronaut seats on a Blue Origin flight.Together, they show how the future of space can be shared by many.

SpaceCoin and DePIN, Not Just Bitcoin, in OrbitSpaceCoin’s vision is simple but radical. It aims to create a network of satellites that transmit blockchain transactions directly through space instead of relying on Earth’s internet. In a recent test, SpaceCoin successfully transmitted data between continents through satellite link alone. That data was not just a signal; it was a blockchain record sent across orbit.

This idea belongs to a new category called Decentralized Physical Infrastructure Networks, or DePIN. These projects use blockchain to power real-world infrastructure rather than purely digital systems. SpaceCoin’s network could serve remote regions, censored areas, and space-based devices that need secure communication without dependence on terrestrial internet.

SpaceCoin at Token 2049 showing how DePIN works even in Space.

Sandy Carter

The implications are enormous.

In chatting with Taekyung Oh, Founder and CEO of SpaceCoin, at Token 2049, he told me that “Space is the ultimate decentralized frontier. With DePIN, we are turning satellites into nodes of a global network where connectivity, computation, and coordination happen beyond borders and even beyond Earth.”

If blockchain can operate from orbit, transactions, identities, and governance systems become independent of Earth’s limitations. A space-based blockchain could enable global connectivity, resilient to censorship or natural disasters, and ready for the era of interplanetary communication. The challenges remain significant such as satellite costs, regulatory issues, and reliability, but the concept of a blockchain that literally reaches for the stars is no longer science fiction.

Taekyung Oh, Founder and CEO of SpaceCoin, on stage at Token 2049

Sandy Carter

From Bitcoin to the Moon: Copernic Space and the Tokenized Space EconomyIf SpaceCoin provides the infrastructure, Copernic Space brings ownership and the financial infrastructure that powers this new economy. Connecting real-world space assets to global capital markets through blockchain technology, the company is pioneering the tokenization of missions, payloads, and even digital identities to transform how space assets are represented, financed, and traded.

Did you know that Copernic Space partnered with SpaceChain to create a commercial marketplace for tokenized space assets? This partnership built on SpaceChain’s earlier work proving that blockchain starting with Bitcoin that could operate off-planet.

And recently, in collaboration with Unstoppable Domains (my employer), Copernic launched the .LUNAR domain extension, the first domain to be tied to real space missions. Each .LUNAR badge will be sent to the Moon on a scheduled mission in 2026-2027. That makes every domain a tokenized real-world asset linked to space. Owning one means holding a verified piece of digital identity that will literally travel beyond Earth.

Copernic Space has already demonstrated how this model works in practice. Its already commercialized rockets and its first Moon Mission earlier this year sold out with over 2,000 tokenized payloads of individuals and companies landing on the Moon, generating revenue and delivering returns to early participants.

Grant Blaisdell, CEO of Copernic Space, is a pioneer in Decentralized Space.

Copernic Space

In chatting with Grant Blaisdell, CEO of Copernic Space, he told me that “decentralization gives space back to humanity. For the first time, people everywhere can own a small but meaningful stake of what happens beyond Earth. By combining blockchain with space missions and ventures, we are creating a transparent, participatory ecosystem where the next great discoveries belong to everyone, not just a few institutions.”

Copernic describes itself as a marketplace for buying, selling, and investing in tokenized space ventures. This model opens the door for individuals to participate in the space economy through blockchain-based ownership. The idea is to turn space into an open and accessible market that anyone can take part in. It redefines how we think about digital property. Instead of owning a website, you might own a domain that represents a payload on a rocket, a satellite, or a lunar mission.

But this goes beyond collectibles. By allowing fractional ownership of real missions and infrastructure, Copernic Space makes participation in the space economy more transparent, liquid, and inclusive. While regulations around space ownership are still evolving, the shift is already underway.

For the first time, space is becoming a market that belongs to everyone, not just governments and large corporations.

TON, SERA, and the New Space Democracy.
While SpaceCoin builds infrastructure and Copernic focuses on assets, TON is opening direct access to space. The TON Foundation, the organization behind the blockchain that powers Telegram, has partnered with the Space Exploration and Research Agency (SERA) to launch Mission Control.

This program uses blockchain to select real civilian astronauts for a Blue Origin flight through an on-chain voting system.

SERA has secured six seats on the upcoming New Shepard mission, planned for 2026. Five are reserved for citizens from underrepresented countries such as India, Nigeria, Brazil, Thailand, and Indonesia.

The sixth seat will go to a global participant chosen through voting on the TON blockchain. Participants use the TON wallet integrated in Telegram to earn points and cast votes. Every vote is recorded on-chain for transparency and fairness.

Max Crown, President and CEO of TON Foundation, a pioneer in the next generation of decentralized space.

Max Crown

"SERA isn’t another crypto project launch, it’s truly a one-of-a-kind initiative. It feels more like an experiment in what happens when crypto collides with an experience-driven, participatory culture," said Max Crown, President and CEO of TON Foundation. "They’re literally putting people into space, and if you’ve got Telegram and a Wallet, you can be part of it. It’s wild. I’ve always believed that people don’t connect with how tech works. They connect with what it does, and how it makes them feel. That’s what matters. We’re not talking about using tech to change lives. We’re actually doing it. This is the moment blockchain shifts from just being technology to becoming an experience."

This initiative is historic. It marks the first time that blockchain technology will directly influence who gets to travel to space. Instead of government committees or corporate sponsors, access is being opened to a global audience. TON calls it “space democracy,” where users earn their chance to go to space by participating in a transparent, tokenized process.

The significance goes beyond one mission.

It demonstrates how blockchain can extend inclusion from financial systems to space exploration. TON’s integration with Telegram gives it a vast audience, bringing the dream of space closer to billions of people. It is not just about technology; it is about participation.

What’s Ahead for Decentralized Space With Bitcoin And Blockchain?
The path forward is not without obstacles. Regulation remains the biggest unknown.

Questions about who governs tokenized lunar assets or how liability works in orbit have no clear answers. Technical hurdles such as satellite lifespan, launch cost, and communication latency will test every innovation.

Market adoption also depends on proving real utility beyond hype.

There are ethical questions as well. Space must not become another venue for inequality or exploitation. If blockchain opens space participation, it must do so fairly and sustainably. The emerging industry will need to balance ambition with responsibility.

Despite the challenges, the direction is unmistakable.

The space economy is expanding rapidly, and blockchain is becoming part of its infrastructure. SpaceCoin, Copernic Space, and TON are demonstrating how decentralization can make the final frontier more open and inclusive.

This matters because it signals a shift in power and possibility. The same technologies that once made finance more inclusive are now doing the same for exploration and discovery.

As these projects evolve, we may soon witness the first blockchain transaction from orbit, the first domain that lands on the Moon, and the first astronaut chosen entirely by a decentralized vote.

The gap between cyberspace and outer space is closing. The blockchain and bitcoin revolution has officially left Earth’s orbit.

Hyperscale Data revealed that the value stored in its Bitcoin treasury now represents around 66% of the company’s total market capitalization based on the previous closing stock price.

Summary

Hyperscale Data’s Bitcoin holdings have reached around 150.21 BTC ($16.3 million) through mining and open-market purchases, with $43.7 million in additional funds.
The company aims to build a $100 million Bitcoin treasury, equivalent to 100% of its market capitalization, reporting weekly progress. So far, it has managed to make it into the top 100 public companies ranked by Bitcoin holdings.

According to a press release shared by the company, the firm’s Bitcoin treasury holds assets and funds to be allocated for purchases amounting to approximately $60 million. The company claims that this amount represents about 66% of the company’s total market cap, which is stated as $75 million according to Bitcoin Treasuries.

As of Oct. 19, the company’s Bitcoin (BTC) treasury subsidiary Sentinum reportedly held about 150.21 Bitcoin ($16.2 million). This amount consists of Bitcoin acquired from mining operations, which is 32.632 BTC or equal to $3.52 million, as well as Bitcoin purchased from the open-market.

So far, the company has purchased as much as 117.58 BTC. Its latest purchase took place during the week of Oct. 19, when the firm bought 15.88 BTC. Based on the Bitcoin closing price of $108,666 on October 19, 2025, these holdings were valued at approximately $16.3 million.

Hyperscale Data’s total Bitcoin holdings have reached $60 million in value | Source: Bitcoin Treasuries
Moreover, the company claims to have allocated around $43.7 million in corporate funds for Sentinum to buy more Bitcoin on the open-market. The company stated that it plans to keep investing funds using what it calls a “measured dollar-cost averaging approach” that aims to limit the impact of market fluctuations while also increasing the value of its long-term reserve holdings.

“Volatility in Bitcoin’s price has provided meaningful opportunities to build our position methodically and at favorable long-term averages,” said Executive Chairman of Hyperscale Data Milton “Todd” Ault III in his statement.

Hyperscale Data’s plan to hold 100% of its market cap in BTC
Hyperscale Data stated that it will continue acquiring more Bitcoin to fulfill its long-term goal of building up a Bitcoin treasury with a value that matches 100% of its market capitalization. As part of its broader digital asset treasury strategy, it aims to stockpile as much as $100 million worth of Bitcoin from open-market purchases and self-mined BTC.

“Hyperscale will continue to issue weekly reports every Tuesday morning detailing its Bitcoin holdings as it advances toward its $100 million DAT target,” said the firm in its official statement.

According to data from Bitcoin Treasuries, Hyperscale Data has only been acquiring BTC for less than a month. It started holding BTC in September 23 of this year. So far, its Bitcoin holdings have reached 130.8 BTC or equal to $14.18 million. With an average cost of $115,460, the company has accumulated a loss of about 6.02% after the value of Bitcoin plummeted below $110,000.

Compared to larger and more established Bitcoin treasury companies like Strategy, Metaplanet, Tesla and Galaxy Digital, it still has a long way to go. However, it has managed to make it into the top 100 public companies that hold Bitcoin despite its late start. Bitcoin Treasuries has ranked Hyperscale Data in 98th place with 131 BTC, beating Mac House and Bitcoin Depot.

At press time, Bitcoin has dropped 2.5% in the past 24 hours, continuing its downward trend of 2.75% within the past week. The largest cryptocurrency by market cap is currently trading hands at $108,153 as it attempts to climb back up to the $110,000 threshold.

Bitcoin ( BTC) briefly dropped to $107,460 on Oct. 21, erasing recent gains and pushing weekly losses to nearly 3%. SpaceX's $270 Million Treasury Transfer In the early hours of Oct. 21, bitcoin ( BTC) briefly dropped to $107,460 before recovering above $108,000.

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On Oct. 21, bitcoin traded at $108,463 to $109,421 over the last hour, with a 24-hour price range between $107,557 and $111,555. The market capitalization stood at $2.16 trillion, while trading volume over the same period totaled $58.95 billion.

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High-profile researchers are leaving the EF, such as Dankrad Feist, who is joining Tempo, the L1 incubated by Stripe.
A former lead developer revealed a salary of $625K over six years (pre-tax), described as “insanely low.”
Polygon CEO Sandeep Nailwal criticized the EF for its lack of support for L2s and the ecosystem’s bad “vibe.”

The Ethereum Foundation (EF) is facing strong controversy this week. It faces severe criticism over its compensation structure and a growing disconnect from the ecosystem it is supposed to lead. This situation has provoked a notable “brain drain,” with key developers and researchers abandoning the organization.

The trigger for this controversy was the departure of Dankrad Feist. He is a long-standing researcher at the EF, who announced his departure to join Tempo, a new Layer 1 (L1) blockchain incubated by Stripe and with considerable financial backing.

Feist’s departure is not an isolated incident. The main catalyst for the churn is salaries. Peter Szilagyi, a former lead developer at the EF, recently revealed that his total compensation for six years of work was $625,000, pre-tax.

This figure was described by multiple players in the sector, including developers from rival chains like Solana, as “insanely low” compared to current market rates for talent of that caliber. This brain drain is especially concerning as new corporate chains, like Tempo, actively seek to compete for Ethereum’s market share.

Ecosystem Misalignment and Internal Criticism
Dissatisfaction within the Ethereum community goes beyond paychecks. Internal sources and prominent ecosystem figures denounce a lack of “vibe” and a deep strategic misalignment between the Ethereum Foundation and key protocols.

Sandeep Nailwal, CEO of Polygon, one of Ethereum’s main L2s, publicly expressed his frustration, stating that the EF has never supported Layer 2 solutions. Nailwal went so far as to describe the Ethereum community as a “shit show,” where massive contributions to the ecosystem are not valued.

This is not the first crisis of this type for the foundation. Earlier in the year, the EF was forced to restructure its leadership to improve ecosystem alignment, starting to actively use applications like Aave and Morpho. However, these measures seem to have been insufficient.

In an apparent effort to control the narrative, Vitalik Buterin, co-founder of Ethereum, publicly praised the contributions of Polygon and Sandeep. Meanwhile, the price of ETH has fallen slightly below $4,000, although market sentiment remains “neutral” despite the community turmoil.

Last week, Ripple announced a $1 billion acquisition of GTreasury, showing the growing demand for its technology among major financial institutions. The goal behind this deal is to help Ripple expand deeper into traditional finance by combining blockchain technology with existing banking systems.

However, CIO at SWIFT, Tom Zschach, claimed that Ripple lacks client trust, regulatory capital, and settlement access. His comments quickly drew a response from crypto lawyer Bill Morgan, who called the criticism unfair and inconsistent.

Ripple’s Progress in FinanceMorgan explained that Tom’s statements contradict themselves. On one hand, Tom says banks are moving ahead by adding digital asset infrastructure into their treasury systems. On the other, he criticizes Ripple for doing the same thing.

Ripple’s new acquisition, GTreasury, already serves 1,000 clients in more than 160 countries. This, he said, is exactly what banks are aiming for. He further noted that Ripple has applied for a U.S. national bank charter, which would allow it to operate as a fully regulated bank.

He added, “It seems Ripple is doing what he says the banks are doing by embedding digital asset infrastructure into an existing treasury ecosystem. One unified platform.”

Ripple Steps Closer to Mainstream FinanceRipple has clearly evolved from being just a blockchain company to becoming a regulated financial player. With its XRP-based cross-border payment solutions and the clarity it received after the SEC lawsuit dismissal, interest from large financial institutions continues to grow.

The GTreasury acquisition is Ripple’s third major deal in 2025, following the purchases of Hidden Road and Rail. These partnerships with banks and payment providers highlight Ripple’s growing role in building real-world financial solutions through blockchain technology.

Ripple CEO Brad Garlinghouse has repeatedly said that his goal is to connect traditional finance with the world of digital assets. With this latest move, Ripple seems closer than ever to achieving that vision.

Trust with CoinPedia:CoinPedia has been delivering accurate and timely cryptocurrency and blockchain updates since 2017. All content is created by our expert panel of analysts and journalists, following strict Editorial Guidelines based on E-E-A-T (Experience, Expertise, Authoritativeness, Trustworthiness). Every article is fact-checked against reputable sources to ensure accuracy, transparency, and reliability. Our review policy guarantees unbiased evaluations when recommending exchanges, platforms, or tools. We strive to provide timely updates about everything crypto & blockchain, right from startups to industry majors.

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October 21, 2025 07:30 ET

 | Source:

BriaCell Therapeutics Corp.

Collaboration with MSK’s Therapeutics Accelerator Program includes manufacturing, IND and clinical development support of the Bria-OTS+™ platform, which includes Bria-BRES+™ for breast cancer
PHILADELPHIA and VANCOUVER, British Columbia, Oct. 21, 2025 (GLOBE NEWSWIRE) -- BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW, BCTXZ), (TSX: BCT) (“BriaCell” or the “Company”), a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care, is pleased to announce a collaboration with Memorial Sloan Kettering Cancer Center’s (MSK’s) Therapeutics Accelerator Cohort program to accelerate the clinical development of Bria-OTS+, BriaCell’s next generation personalized off-the-shelf immunotherapy, for multiple cancer indications including metastatic breast cancer, prostate cancer, and other cancers.

The collaboration starts with manufacturing, IND development and clinical protocol support for a Phase 1 clinical trial with Bria-BRES+, BriaCell’s next generation personalized immunotherapy for patients with breast cancer under the Bria-OTS+ platform.   The partnership expands on BriaCell’s previously-announced selection into MSK’s accelerator program.

As one of the world’s foremost cancer research and treatment institutions, MSK has more than 135 years of leadership in patient care, education and discovery. Through the MSK Therapeutics Accelerator, MSK’s therapeutic-based strategic collaboration program, BriaCell will obtain access to MSK’s clinical and institutional expertise, including cell therapy manufacturing, Investigational New Drug (IND) preparation and submission and clinical development to expedite development of the Bria-OTS+ platform.

“We are thrilled to collaborate with MSK’s scientific and clinical experts to address the urgent unmet medical need of many thousands of metastatic breast cancer patients,” stated Dr. William V. Williams, BriaCell’s President and CEO.

“We are honored to be working with the team of cancer specialists at MSK,” noted Miguel Lopez-Lago, PhD, BriaCell’s Chief Scientific Officer. “This collaboration with MSK will accelerate the development of our advanced personalized off-the-shelf immunotherapy platform, Bria-OTS+, which we believe has the potential to transform cancer care and significantly improve patients’ lives through its unique mechanism of action.”

“We look forward to working with BriaCell through MSK’s Therapeutics Accelerator to help advance this next-generation personalized immunotherapy into the clinic.  Collaborations like this are essential to translating promising scientific innovations into potential new treatment options for patients,” commented Shanu Modi, MD, Breast Medical Oncologist and Attending Physician at MSK.

About BriaCell Therapeutics Corp.

BriaCell is a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care. More information is available at https://briacell.com/.

About MSK Therapeutics Accelerator

Through its Therapeutics Accelerator program, MSK partners with biotechnology companies to help advance innovative cancer therapeutics from early development through the clinic. By combining the resources of cutting-edge healthcare companies with MSK’s world-renowned clinical and scientific expertise, the program fosters collaborations aimed at improving the treatment and management of cancer. For more information, see here: Commercialization Accelerators & Programs: MSK Therapeutics Accelerator | Memorial Sloan Kettering Cancer Center .

Memorial Sloan Kettering (MSK) has institutional financial interests related to BriaCell.

Safe Harbor

This press release contains “forward-looking statements” that are subject to substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press release may be identified by the use of words such as “anticipate,” “believe,” “contemplate,” “could,” “estimate,” “expect,” “intend,” “seek,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “target,” “aim,” “should,” “will,” “would,” or the negative of these words or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements in this press release, including statements regarding the Company’s beliefs that the collaboration with the Memorial Sloan Kettering Cancer Center could advance the clinical development of Bria-OTS+; the specific areas that the MSK Therapeutics Accelerator Cohort will explore; the Company’s access to MSK’s expertise and institutional resources; and the Company’s beliefs regarding Bria-OTS+’s potential to transform cancer care and offer meaningful advances in efficacy and safety for thousands of patients, are based on assumptions as to future events that may not prove to be accurate. These and other risks and uncertainties are described more fully under the heading “Risks and Uncertainties” in the Company’s most recent Management’s Discussion and Analysis, under the heading “Risk Factors” in the Company’s most recent Annual Information Form and under “Risks and Uncertainties” in the Company’s other filings with the Canadian securities regulatory authorities and the U.S. Securities and Exchange Commission, all of which are available under the Company’s profiles on SEDAR+ at www.sedarplus.ca and on EDGAR at www.sec.gov. Forward-looking statements contained in this announcement are made as of this date and BriaCell Therapeutics Corp. undertakes no duty to update such information except as required under applicable law.

Neither the Toronto Stock Exchange nor its Regulation Services Provider (as that term is defined in the policies of the Toronto Stock Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact Information

Company Contact:
William V. Williams, MD
President & CEO
1-888-485-6340
[email protected] 

Investor Relations Contact:
[email protected]

MIAMI, Oct. 21, 2025 (GLOBE NEWSWIRE) -- Wrap Technologies, Inc. (NASDAQ: WRAP) (“Wrap” or the “Company”), a global leader in innovative public safety and unmanned systems technology, today announced the formation of Wrap Federal, LLC (“Wrap Federal”) a wholly owned subsidiary of the Company dedicated to supporting U.S. federal government clients in the Department of Defense (DoD), Department of Homeland Security (DHS), and other federal agencies.

The formation of Wrap Federal marks a significant milestone in the Company’s ongoing transformation, establishing a dedicated operating entity intended to meet the strict compliance, contracting, and operational standards of the federal marketplace.

Wrap Federal strives to fully align with Defense Contract Audit Agency (DCAA) readiness standards and to offer options to support classified contracting, and uphold compliant accounting, security, and operational protocols essential for collaboration with the nation’s leading defense and homeland security organizations.

As part of its federal strategy, Wrap Federal aims to collaborate with established prime contractors and contracting mechanisms to potentially streamline current contracting pathways and speed up access to mission-critical programs within the DoD, DHS, and other federal agencies. This strategic approach is expected to enable Wrap Federal to integrate its systems into existing federal frameworks, supporting the Company’s goal of becoming a fully integrated federal public safety and defense technology enterprise.

Core Offerings: Non-Lethal and Counter-UAS Solutions

Wrap Federal is expected to concentrate on two main technology sectors that support mission safety, readiness, and compliance across federal operations.

BolaWrap 150 Non-Lethal, Hands-on Tool: A proven device, deployed to over 1,000 agencies worldwide, designed to provide federal law enforcement, corrections, and military police with a safe, pain-free alternative to manage resistance and reduce use-of-force incidents.Counter-UAS and Drone Interdiction Systems: Building on Wrap’s proprietary entanglement and deployment technologies, our CUAS and DFR-X (Drone as First Responder and Interdiction) platform transforms traditional drone operations from passive observation to active, non-lethal response. Designed for integration with existing drone platforms, the Company's CUAS platform is designed to down aerial threats with a non-lethal payload, while the DFR-X platform enables non-lethal early interdiction to deter, delay, or neutralize human threats, with the goal of enhancing homeland security, border protection, and critical infrastructure defense missions in the sky and on the ground. Positioned for Federal Growth and Compliance

“The creation of Wrap Federal marks an important expansion of our mission, to make every encounter safer, into the federal and defense landscape,” said Scot Cohen, Chief Executive Officer of Wrap. “We believe we are building the foundation to meet the federal government’s growing demand for integrated non-lethal and counter-UAS solutions, supported by the highest levels of regulatory, cybersecurity, and operational compliance.”

Jared Novick, President and Chief Operating Officer of Wrap, added: “Wrap Federal is expected to be structured with the systems, clearances, and governance necessary to support DCAA-auditable contracts, classified engagements, and partnerships with both prime contractors and federal agencies. We believe this step reflects our continued evolution from a product company into a fully integrated public safety and defense technology enterprise.”

About Wrap Technologies, Inc.

Wrap Technologies, Inc. (Nasdaq: WRAP) a global leader in innovative public safety technologies and non-lethal tools, delivering cutting-edge technology with exceptional people to address the complex, modern day challenges facing public safety organizations.

Wrap's complete public safety portfolio includes the non-lethal BolaWrap 150 device, WrapReality™ immersive training platform, WrapVision™ body-worn camera system, WrapTactics™ training programs, and next-generation CUAS solutions like PAN-DA and the 1KC Kinetic Anti-Drone Cassette, all of which supports the Company's mission to provide safer, scalable, and cost-effective technologies for public safety, defense, and critical infrastructure markets. Wrap’s BolaWrap® 150 solution leads in pre-escalation intended to provide law enforcement with a safer choice for nearly every phase of a critical incident. This innovative, patented device deploys a multi-sensory, cognitive disruption that leverages sight, sound and sensation to expand the pre-escalation period and gives officers the advantage and critical time to manage non-compliant subjects before resorting to higher-force options. The BolaWrap 150 is not pain-based compliance. It does not shoot, strike, shock, or incapacitate, instead, it helps officers strategically operate pre-escalation on the force continuum, reducing the risk of injury to both officers and subjects. Used by over 1,000 agencies across the U.S. and in 60 countries, BolaWrap® is backed by training certified by the International Association of Directors of Law Enforcement Standards and Training (IADLEST), reinforcing Wrap’s commitment to public safety through cutting-edge technology and expert training.

Wrap Reality™ VR is a fully immersive training simulator to enhance decision-making under pressure.

As a comprehensive public safety training platform, it provides first responders with realistic, interactive scenarios that reflect the evolving challenges of modern law enforcement. By offering a growing library of real-world situations, Wrap Reality™ is intended to equip officers with the skills and confidence to navigate high-stakes encounters effectively, which we believe leads to safer outcomes for both responders and the communities they serve.

WrapVision is an all-new body-worn camera and evidence management system built for efficiency.

Designed for efficiency, security, and transparency to meet the rigorous demands of modern law enforcement, WrapVision captures, stores, and helps manage digital evidence, ensuring operational security, regulatory compliance, and enhanced video picture quality and field of view.

The WrapVision camera, powered by IONODES, boasts streamlined cloud integration and final North American assembly, with a critical made-in-America roadmap projected for early 2026. This track helps ensure data integrity and helps eliminate critical concerns over unauthorized access or foreign surveillance risks.

Trademark Information

Wrap, the Wrap logo, BolaWrap®, Wrap Reality™ and Wrap Training Academy are trademarks of Wrap Technologies, Inc., some of which are registered in the U.S. and abroad. All other trade names used herein are either trademarks or registered trademarks of the respective holders.

Cautionary Note on Forward-Looking Statements – Safe Harbor Statement

This release contains “forward-looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Words such as “expect,” “anticipate,” “should”, “believe”, “target”, “project”, “goals”, “estimate”, “potential”, “predict”, “may”, “will”, “could”, “intend”, and variations of these terms or the negative of these terms and similar expressions are intended to identify these forward-looking statements. Moreover, forward-looking statements are subject to a number of risks and uncertainties, many of which involve factors or circumstances that are beyond the Company’s control and include, but are not limited to, statements relating to Wrap Federal’s ability to obtain DoD and DHS contracts and its ability to meet the operational standards of the federal marketplace and DCAA and to integrate its systems into existing federal frameworks, Wrap’s Project MERLIN-1 initiative and plans for commercialization, and the Wrap’s plans to expand into CUAS aerial defense and future UAS public safety missions. The Company’s actual results could differ materially from those stated or implied in forward-looking statements due to a number of factors, including but not limited to: the Company’s ability to maintain compliance with the Nasdaq Capital Market’s listing standards; the Company’s ability to successfully implement training programs for the use of its products; the Company’s ability to manufacture and produce products for its customers; the Company’s ability to develop sales for its products; the market acceptance of existing and future products; the availability of funding to continue to finance operations; the complexity, expense and time associated with sales to law enforcement and government entities; the lengthy evaluation and sales cycle for the Company’s product solutions; product defects; litigation risks from alleged product-related injuries; risks of government regulations; the business impact of health crises or outbreaks of disease, such as epidemics or pandemics; the impact resulting from geopolitical conflicts and any resulting sanctions; the ability to obtain export licenses for counties outside of the United States; the ability to obtain patents and defend intellectual property against competitors; the impact of competitive products and solutions; and the Company’s ability to maintain and enhance its brand, as well as other risk factors mentioned in the Company’s most recent annual report on Form 10-K, subsequent quarterly reports on Form 10-Q, and other Securities and Exchange Commission filings. These forward-looking statements are made as of the date of this release and were based on current expectations, estimates, forecasts, and projections as well as the beliefs and assumptions of management. Except as required by law, the Company undertakes no duty or obligation to update any forward-looking statements contained in this release as a result of new information, future events or changes in its expectations.

Investor Relations Contact:

(800) 583-2652
[email protected]

October 21, 2025 07:30 ET

 | Source:

First American Uranium Inc.

Vancouver, BC, Oct. 21, 2025 (GLOBE NEWSWIRE) -- First American Uranium Inc. (CSE: URM) (FSE: IOR) (OTCPK: FAUMF) (“First American”, or the “Company”) is pleased to announce the appointments of the Hon. Kerry-Lynne D. Findlay and Joseph A. Carrabba to the Board of Directors of the Company (the “Board”).

Ms. Findlay is a Canadian lawyer, senior business consultant and advisor known for decades of leadership in law, politics, and public service. A former federal Cabinet Minister, she has served as Canada’s Minister of National Revenue, Associate Minister of National Defence, and Parliamentary Secretary to Justice. She represented British Columbia in the House of Commons for more than a decade, including roles as Chief Opposition Whip and Shadow Minister for National Defence and for Environment and Climate Change.

Before entering politics, Ms. Findlay built a distinguished legal career as a civil litigator at all levels of court, including the Supreme Court of Canada, and as an Administrative Law Judge on the Canadian Human Rights Tribunal. She has been recognized with numerous honours, including appointment as King’s Counsel, the Canadian Bar Association’s Cecilia I. Johnstone Award, and the YWCA Woman of Distinction Award.

Mr. Carrabba is a corporate mining professional with a proven track record of operating, growing, and leading emerging natural resources companies. He is the former Chairman, President and Chief Executive Officer of Cliffs Natural Resources Inc., where he served in executive capacities from 2005 to 2013. 

Prior to joining Cliffs Natural Resources Inc., Mr. Carrabba gained broad experience in the mining industry throughout Canada, the United States, Asia, Australia and Europe. He served for over 20 years in a variety of leadership capacities at Rio Tinto, a global mining company, including as President and Chief Operating Officer of Rio Tinto’s Diavik Diamond Mines, Inc. in the Northwest Territories. Mr. Carrabba has also served on numerous boards of several listed companies, including Key Bank, Lithium-X, Fura Gems, Newmont Mining, Timken Steel, AECON, and NioCorp.

“We’re excited to welcome Kerry-Lynne and Joseph to the Board as we look to expand our reach in the critical minerals and rare earth elements space,” said Murray Nye, Chief Executive Officer of First American. “Both of their strong operational track records and skillsets deepen our bench strength significantly. Kerry-Lynne’s extensive knowledge and experience navigating key Canadian government institutions and Joseph’s tenures leading emerging natural resource projects through exploration & development –in particular, his tenure at NioCorp – will play instrumental roles in our ability to form strategic government partnerships and funding as we look to advance our rare earth elements projects in Quebec.”

ABOUT FIRST AMERICAN URANIUM INC.

First American Uranium Inc. is a North American mineral exploration company focused on the acquisition and development of precious, base, and critical mineral assets. Its portfolio includes the Silver Lake property in British Columbia’s Omineca Mining Division and a recently acquired land package in Quebec’s Grenville Province. The Quebec properties add exposure to rare earth elements (REE), niobium (Nb), and nickel-copper (Ni-Cu) occurrences, expanding the Company’s footprint into critical minerals that are strategically important for energy and defense applications.

ON BEHALF OF THE BOARD OF DIRECTORS:

Murray Nye
Chief Executive Officer

1055 West Georgia Street, Suite 1500
Vancouver, BC V6E 0B6
Canada

For further information, please contact:

Murray Nye, CEO
Email: [email protected]
Phone: +1 (604) 416-4099

CSE:URM
OTCPK:FAUMF
FSE:IOR

The Canadian Securities Exchange does not accept responsibility for the adequacy or accuracy of this release and has neither approved nor disapproved the contents of this press release.

This news release includes certain statements that may be deemed “forward-looking statements”. All statements in this news release, other than statements of historical facts, that address events or developments that the Company expects to occur, are forward-looking statements. Forward-looking statements are statements that are not historical facts and are generally, but not always, identified by the words “believes”, “expects”, “plans”, “anticipates”, “intends”, “estimates”, “projects”, “potential” and similar expressions, or that events or conditions “will”, “would”, “may”, “could” or “should” occur. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results may differ materially from those in the forward-looking statements. Forward looking statements in this news release include statements respecting: (i) the Grenville Properties and the mineral prospects thereon, and (ii) the Company's planned activities on the Grenville Properties.  Factors that could cause the actual results to differ materially from those in forward-looking statements include the receipt of regulatory approvals, market prices, continued availability of capital and financing, and general economic, market or business conditions. Investors are cautioned that any such statements are not guarantees of future performance and actual results or developments may differ materially from those projected in the forward-looking statements. Forward-looking statements are based on the beliefs, estimates and opinions of the Company’s management on the date the statements are made. Except as required by applicable securities laws, the Company undertakes no obligation to update these forward-looking statements in the event that management's beliefs, estimates or opinions, or other factors, should change.

Lockheed Martin logo is seen in this illustration taken July 26, 2025. REUTERS/Dado Ruvic/Illustration Purchase Licensing Rights, opens new tab

Oct 21 (Reuters) - U.S. defense contractor Lockheed Martin raised its 2025 forecast for revenue and profit on Tuesday, driven by sustained demand for its fighter jets and munitions amid escalating geopolitical tensions.

Shares of the company rose 3.2% before the bell.

Sign up here.

Weapons makers are benefiting from surging demand for arms as a result of simmering conflicts in the Middle East and a protracted Russia-Ukraine war.

Lockheed, which makes the F-35 stealth fighters, said its aeronautics segment sales jumped 11.9% to $7.26 billion in the third quarter.

The program secured a long-awaited

$12.5 billion contract, opens new tab from the Pentagon last month, for a total of 296 F-35 jets.

Lockheed has also clinched some large agreements recently, including an about $11 billion navy contract to build up to 99 CH-53K King Stallion helicopters, and a nearly $10 billion contract for Patriot missiles.

The commitments underscore a growing need for the U.S. government and its allies to replenish stockpiles and load up on new weapons.

Lockheed, the largest defense contractor in the world, is also vying for a slice of the Trump administration's $175 billion marquee Golden Dome missile shield, for which the Pentagon began doling out contracts last month.

The company's total revenue rose 8.8% to $18.61 billion in the third quarter from $17.1 billion a year ago. Profit per share came in at $6.95.

It now expects a profit of $22.15 to $22.35 per share for 2025, compared with its previous estimate of $21.70 to $22.00.

The company also raised the lower end of its sales outlook to $74.25 billion from $73.75 billion, while maintaining the higher end at $74.75 billion.

Reporting by Utkarsh Shetti in Bengaluru and Mike Stone in Washington; Editing by Shinjini Ganguli

Our Standards: The Thomson Reuters Trust Principles., opens new tab

Mike Stone is a Reuters reporter covering the U.S. arms trade and defense industry. Most recently Mike has been focused on the Golden Dome missile defense shield. Mike also spends a lot of his time writing on Ukraine and how industry has adapted, or faltered as it supports that conflict. Mike, a New Yorker, has extensively covered how the U.S. has supplied Ukraine with weapons, the cadence, decisions and milestones that have had battlefield impacts. Before his time in Washington Mike’s coverage focused on mergers and acquisitions for oil and gas companies, financial institutions, defense companies, consumer product makers, retailers, real estate giants, and telecommunications companies.

Mikra product lineup features new formulations and fresh branding at accessible prices to attract U.S. consumers and drive sustainable growth

October 21, 2025 07:35 ET

 | Source:

Lifeist Wellness Inc.

TORONTO, Oct. 21, 2025 (GLOBE NEWSWIRE) -- Lifeist Wellness Inc. (“Lifeist” or the “Company”) (TSX.V: LFST; OTCQB: LFSWF; FRANKFURT: M5B0) announces the return of its Mikra brand to Amazon.com in the United States with a lineup featuring new performance-based products, refreshed formulations and attractive packaging designed to elevate customer engagement. The new Mikra storefront can be found here.

“We’re making it easier for U.S. consumers to discover and shop Mikra’s growing portfolio of performance-enhancing products,” said Andrea Judge, CEO of Lifeist. “Our revitalized brand and expanded portfolio of innovative formulations are shaped by consumer insights and market learnings. We’re also offering lower price entry options to encourage trial and repeat purchasing, which aligns with Amazon’s consumer shopping behavior.”

Judge added, “Relaunching our Amazon storefront is about more than elevating the customer experience—it’s a critical step in demonstrating proof of demand to support potential wholesale partnerships and expansion into additional retail channels.”

Mikra’s complete lineup of performance-focused products will be rolled out on Amazon.com as inventory becomes available.

About Mikra

Mikra is a performance-focused supplement brand built around a simple idea: the mind leads, and the body follows. Through targeted, science-backed formulations, Mikra is creating a new standard for what it means to support total human performance—starting with cognitive and emotional resilience.

About Lifeist Wellness Inc.

Sitting at the forefront of the post-pandemic wellness revolution, Lifeist acquires, integrates, and builds top wellness brands that enhance global well-being. Lifeist’s key asset is its U.S. biosciences subsidiary Mikra Cellular Sciences Inc. (“Mikra”), a biosciences and consumer wellness company focused on developing and selling innovative wellness products. For more information, visit: www.lifeist.com.

For further information, please contact:

Andrea Judge, CEO
Lifeist Wellness Inc.
Phone: 604-901-8434
Email: [email protected]

Matt Coltura
Investor Relations
Phone: 778-886-6200
Email: [email protected]

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release or has in any way approved or disapproved of the contents of this press release.

Source: Lifeist Wellness Inc.

October 21, 2025 7:35 AM EDT | Source: Thunder Gold Corp.
Thunder Bay, Ontario--(Newsfile Corp. - October 21, 2025) - Thunder Gold Corp. (TSXV: TGOL) (FSE: Z25) (OTCQB: TGOLF) ("Thunder Gold" or the "Company") is pleased to announce that Micon International Limited ("MICON") has been contracted to complete an NI 43-101 Mineral Resource Estimate ("MRE") at the Company's 100%-owned, 2,500-hectare, Tower Mountain Gold Property, located 50 kilometres west of Thunder Bay, Ontario.

The MRE shall evaluate the UV, Bench, Ellen, A, 110 and 3738 targets, arrayed along the western contact of the Tower Mountain Intrusive Complex ("TMIC") over a total strike length of 1,800 metres representing 20% of the total strike length surrounding the TMIC. A total of 161 diamond drill holes (35,389 metres), have been completed in this area to test these targets (Reference Figure 1.0).

Key Highlights:

Estimated MRE completion January 2026.

MRE to evaluate the western contact, accounting for only 20% of the TMIC.

MRE to define a lower-capex gold resource that supports a pathway to open-pit production.

Phase Three Drill Program is on schedule with estimated completion October 31, 2025.

Phase Three results are estimated to be received by January 15, 2026.

Rising gold prices and the project's infrastructure advantages support rapid advancement toward development.

The Company's Phase 3 drill program (2,000 metres), currently 50% complete, is scheduled to conclude October 31, 2025. Approximately 70% of the Phase Three program targets gaps in the Company's conceptual exploration model for the western edge of the TMIC. Drill results are anticipated 4-6 weeks after the program terminates.

Wes Hanson, President and CEO states, "Initiating an NI 43-101 Mineral Resource Estimate is a pivotal milestone for Thunder Gold and the Tower Mountain project. Our team has always believed in the asset's scale, continuity and growth potential - and now we are taking the step to validate that conviction through an independent third-party assessment. The MRE will not only provide investors with the confidence we've held for years but will also advance our refined development strategy: to define a lower-capex gold resource that supports a pathway to open-pit production.

Results from our Phase Two drill program clearly demonstrated Tower Mountain's Tier One discovery potential and reinforced our decision to pursue an MRE. They also revealed meaningful opportunities to expand the mineralized footprint along the western TMIC contact through selective drilling, targeting gaps within our predictive model. We expect our Phase Three program to continue demonstrating strong continuity.

With exceptional infrastructure access, extremely low exploration costs and district-scale potential, Tower Mountain stands apart from most projects at this stage. These advantages not only allow us to work faster and more efficiently but also position us as an emerging gold developer capable of advancing meaningfully in the current market. We are eager to capitalize on the rising gold price, accelerate development, and deliver sustained long-term value for our shareholders."

FIGURE 1.0 DIAMOND DRILL PLAN - WESTERN CONTACT AREA - TOWER MOUNTAIN PROPERTY

To view an enhanced version of this graphic, please visit:
https://images.newsfilecorp.com/files/5364/271225_ba3e8a4524b288b2_001full.jpg

Historical drilling has largely focused along the western perimeter of the TMIC defining the UV, Ellen, 3738, Bench, A and 110 targets (Reference Figure 1.0). The targets extend, semi-continuously over 1,800 metres from the 110 target in the south to the UV target in the north.

UV target

Drilling has established gold mineralization along a northwesterly trending corridor measuring 400 metres along strike with an estimated width of 200 metres. Mineralization is interpreted to be sub-vertical and is currently drill-traced from surface to a maximum depth of 300 metres. Historical drilling has been completed to a nominal drill spacing of 25 metres. Mineralization is open to the northwest and at depth.

Ellen target

Drilling has established gold mineralization along a northwesterly trending corridor measuring 100 metres along strike with an estimated width of 200 metres. Mineralization is interpreted to be sub-vertical and is currently drill-traced from surface to a maximum depth of 200 metres. Historical drilling has been completed to a nominal drill spacing of 25 metres. Mineralization remains open at depth and the Ellen target trends into the 3738 target to the southeast.

Bench target

Drilling has established gold mineralization along a northwesterly trending corridor measuring 500 metres along strike with an estimated width of 300 metres. Mineralization is interpreted to be sub-vertical and is currently drill-traced to a maximum depth of 500 metres. Historical drilling has been completed to a nominal drill spacing of 50 metres. Mineralization remains open at depth and is interpreted to transition into the 3738 Target to the northwest. To the southeast, the Bench target is interpreted to be fault offset 200 metres to the southwest, expressed as the 110 target.

3738 target

Drilling has established gold mineralization along a northwesterly trending corridor between the Bench and Ellen Target, an approximate 250 metres along strike with an estimated width of 300 metres. Mineralization sub-crops near surface, is interpreted to be sub-vertical and is currently drill-traced to a maximum depth of 400 metres. Historical drilling has been completed to a nominal drill spacing of 100 metres. Mineralization remains open at depth and is interpreted to transition into the 3738 Target to the northwest. To the southeast, the Bench target is interpreted to be fault offset 200 metres to the southwest, expressed as the 110 Target.

A Target

Drilling has established high grade gold mineralization along a northwesterly trending corridor measuring 150 metres along strike with an estimated width of 100 metres. Mineralization outcrops at surface and is interpreted to be sub-vertical, currently drill-traced to a maximum depth of 125 metres. Historical drilling has been completed to a nominal drill spacing of 25 metres. Mineralization remains open in all directions.

110 Target

Drilling has established gold mineralization along a northwesterly trending corridor measuring 200 metres along strike with an estimated width of 150 metres. Mineralization outcrops at surface and is interpreted to be sub-vertical, currently drill-traced to a maximum depth of 300 metres. Historical drilling has been completed to a nominal drill spacing of 50 metres. Mineralization remains open in all directions.

Infrastructure (Reference Figure 2.0)

The Tower Mountain Property is located 40 kilometres west of the port city of Thunder Bay, ON. The Trans-Canada highway provides year-round access to the property via a 4.0 kilometre secondary road. The main east-west CN rail line, with an existing siding, crosses the secondary road accessing the property. The existing main hydro transmission line is located 2.0 kilometres west of the conceptual pit limit. The Company's conceptual pit limit is currently 2.0 kilometres south of the Matawin River and Trans-Canada highway and 1.5 kilometres from the CN rail line.

FIGURE 2.0 TOWER MOUNTAIN PROPERTY - EXISTING INFRASTRUCTURE

To view an enhanced version of this graphic, please visit:
https://images.newsfilecorp.com/files/5364/271225_ba3e8a4524b288b2_002full.jpg

Quality Assurance and Quality Control

Diamond drilling utilizes NQ diameter tooling. The core is received at the on-site logging facility where it is, photographed, logged for geotechnical, physical properties and geological data. Samples are identified, recorded, and cut in half by wet diamond saw. Half the core is sent for assay at an accredited laboratory with the remaining half core stored on site. A standard sample length of 1.5 meters is typically employed, varying only at major lithological contacts. Certified standards and blanks are randomly inserted into the sample stream and constitute approximately 10% of the sample stream. Certified standards and blank performance is monitored with any failures evaluated and investigated to determine if said failure is a result of error during submission. Any unexplained failures are identified and the five samples preceding and following the failure are re-assayed. In addition, standards and blanks are inserted into the re-assayed interval stream to monitor analytical performance. Samples are shipped to the Activation Laboratories Ltd. facility in Thunder Bay, Ontario, where sample preparation and analyses are completed. All samples are analyzed for gold using a 30-gram lead collection fire assay fusion (FA) with an atomic absorption (AAS) finish. All assay results greater than 5.0 g/t Au are re-assayed using a gravimetric analysis. All assays greater than 30.0 g/t Au are re-assayed using screen metallics where a representative 1000-gram sample is split sieved at 149µm. Assays are performed on the entire +149 µm fraction and two splits of the -149 µm fraction. A final assay is calculated based on the weight of each size fraction.

Qualified Person

Technical information in this news release has been reviewed and approved by Wes Hanson, P.Geo., President and CEO of Thunder Gold Corp., who is a Qualified Person under the definitions established by National Instrument 43-101.

About the Tower Mountain Gold Property

The 100%-owned Tower Mountain Gold Property is located adjacent to the Trans-Canada highway, approximately 50-km west of the international port city of Thunder Bay, Ontario. The 2,500-hectare property surrounds the largest, exposed, intrusive complex in the eastern Shebandowan Greenstone Belt where most known gold occurrences have been described as occurring either within, or proximal to, intrusive rocks. Gold at Tower Mountain is localized within extremely altered rocks surrounding the Tower Mountain Intrusive Complex, a multi-phase, long duration intrusive complex that control gold distribution on the Property. Historical drilling has established anomalous gold extending out from the intrusive contact for over 500 metres along a 1,800-metre strike length, to depths of over 500 metres from surface. The remaining 75% of the perimeter surrounding the intrusion shows identical geology, alteration, and geophysical response, offering a compelling exploration opportunity.

About Thunder Gold Corp.

Thunder Gold is advancing the Tower Mountain Project in Thunder Bay, Ontario - an emerging gold system with the scale, consistency and quality to support a long-life, open-pit operation. Results from our disciplined drill programs have consistently reinforced confidence in the continuity and predictability of the discovery, while highlighting significant potential for expansion across multiple zones of the Tower Mountain Intrusive Complex.

To crystallize this value, Thunder Gold is now advancing toward its first NI 43-101 Mineral Resource Estimate, with the strategic objective of defining a lower-capex, near-surface gold resource that can support a realistic development pathway. This milestone is expected to provide third-party validation of the asset's scale and longevity, while positioning Tower Mountain more competitively among its peers.

With industry-leading drilling costs, existing infrastructure and access to a skilled local workforce, Tower Mountain represents a rare combination of size, scalability and cost-effective growth.

At Thunder Gold, our vision is clear: to unlock a discovery with the potential to become a transformational Canadian gold project - delivering long-term value for shareholders while contributing to the future of Canada's mining industry.

For more information, please visit: www.thundergoldcorp.com.

On behalf of the Board of Directors,

Wes Hanson, P.Geo., President and CEO

NEITHER THE TSX VENTURE EXCHANGE NOR ITS REGULATION SERVICES PROVIDER (AS THAT TERM IS DEFINED IN THE POLICIES OF THE TSX VENTURE EXCHANGE) ACCEPTS RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.

The information contained herein contains "forward-looking information" and "forward-looking statements" within the meaning of applicable securities legislation (collectively, "forward-looking statements"). Forward-looking statements relate to information that is based on assumptions of management, forecasts of future results, and estimates of amounts not yet determinable. All statements, other than statements of historical fact, are forward-looking statements and are based on predictions, expectations, beliefs, plans, projections, objectives and assumptions made as of the date of this news release, including without limitation; anticipated results of geophysical drilling programs, geological interpretations and potential mineral recovery. Any statement that involves discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, assumptions, future events or performance (often but not always using phrases such as "expects", or "does not expect", "is expected", "anticipates" or "does not anticipate", "plans", "budget", "scheduled", "forecasts", "estimates", "believes" or "intends" or variations of such words and phrases or stating that certain actions, events or results "may" or "could", "would", "might" or "will" be taken to occur or be achieved) are not statements of historical fact and may be forward-looking statements.

Forward-looking statements are subject to a variety of risks and uncertainties which could cause actual events or results to differ from those reflected in the forward-looking statements, including, without limitation: risks related to failure to obtain adequate financing on a timely basis and on acceptable terms; risks related to the outcome of legal proceedings; political and regulatory risks associated with mining and exploration; risks related to the maintenance of stock exchange listings; risks related to environmental regulation and liability; the potential for delays in exploration or development activities or the completion of feasibility studies; the uncertainty of profitability; risks and uncertainties relating to the interpretation of drill results, the geology, grade and continuity of mineral deposits; risks related to the inherent uncertainty of production and cost estimates and the potential for unexpected costs and expenses; results of prefeasibility and feasibility studies, and the possibility that future exploration, development or mining results will not be consistent with the Company's expectations; risks related to the gold price and other commodity price fluctuations; and other risks and uncertainties related to the Company's prospects, properties and business detailed elsewhere in the Company's disclosure record. Should one or more of these risks and uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described in forward-looking statements. Investors are cautioned against attributing undue certainty or reliance on forward-looking statements. These forward-looking statements are made as of the date hereof and the Company does not assume any obligation to update or revise any forward-looking statements, other than as required by applicable law, to reflect new information, events or circumstances, or changes in management's estimates, projections or opinions. Actual events or results could differ materially from those anticipated in the forward-looking statements or from the Company's expectations or projections.

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/271225

CANADA - 2025/08/16: In this photo illustration, the Gemini Space Station logo is seen displayed on a smartphone screen. (Photo Illustration by Thomas Fuller/SOPA Images/LightRocket via Getty Images)

SOPA Images/LightRocket via Getty Images

Shares of cryptocurrency exchange Gemini Space Station (NASDAQ: GEMI) have experienced a tumultuous beginning following their highly awaited debut last month. The company set its IPO price at $28 per share, raising several hundred million dollars in the process. Although trading commenced at $37 on the first day, the stock has subsequently dropped to around $20 per share, significantly below its IPO price, influenced partly by the recent crypto selloff and concerns regarding the company’s lack of profitability, as well as a slower than anticipated rate cut cycle by the Federal Reserve. However, with the stock down nearly 25% from its IPO price and its market capitalization at approximately $2.3 billion, is this stock currently a good buy?

If you’re looking for potential upside with reduced volatility compared to individual stocks, the Trefis High Quality portfolio offers an alternative, having outperformed the S&P 500 and achieved returns surpassing 105% since its inception.

Institutional Focused CryptoGemini has established itself as one of the more institutional-grade entities in the crypto industry, providing a diverse array of products beyond its primary exchange. Co-founded by Cameron and Tyler Winklevoss, who are recognized for their legal battle with Mark Zuckerberg concerning Facebook’s beginnings, the company offers a U.S. dollar-backed stablecoin, a crypto rewards credit card, and an NFT studio. Crucially, Gemini provides digital asset custody services, aimed at institutional investors that need secure and compliant infrastructure to manage cryptocurrency at scale.

According to its IPO filings, Gemini manages over $21 billion in assets and serves approximately 10,000 institutions globally. This positioning - centered on regulation, compliance, and infrastructure - lends the exchange a reputation that is quite different from less regulated competitors. However, Gemini’s business model is still largely dependent on a common lever for crypto exchanges: transaction fees on volume-based trades. While the company has effectively diversified into associated services, generating custody fees, credit card interchange fees, and treasury yields from its stablecoin, trading continues to constitute the majority of its revenue. This dependence creates a direct correlation between Gemini’s financial performance and the unpredictable fluctuations of crypto trading activity.

A part of Gemini’s diversification effort is its crypto-linked credit card, which transforms everyday spending into crypto rewards. Beyond creating new revenue streams from interchange fees, the card acts as a customer acquisition tool, as a considerable number of cardholders reportedly go on to use the exchange, thereby nurturing Gemini’s core trading business while enhancing customer engagement.

Growth Slowdown, Profitability Concerns, But There’s Reason For OptimismAt its current market cap, Gemini has a price-to-sales ratio of about 16x projected revenue. This is considered relatively high, especially as its growth trajectory appears to be decelerating. In 2024, revenues increased by roughly 40% to $136 million, but the momentum has significantly slowed, with consensus estimates forecasting growth of only around 22% for this year. In fact, revenues in the first half of 2025 actually fell compared to the same period last year. Profitability also remains a significant issue. Gemini reported substantial losses in 2024, and those losses have continued to escalate. In the first half of 2025 alone, net losses reached $282 million, bringing the total in the trailing 12 months to about $400 million — a sharp increase from $159 million in 2024.

Nevertheless, there are grounds for optimism. Comparatively more established crypto competitor Coinbase, which is anticipated to grow its revenue by around 13% this year, is trading at about 12x projected revenue - not far below Gemini’s ratio. Additionally, Gemini has been receiving increased analyst attention in recent weeks, with most major banks adopting positive or neutral perspectives on the stock. This could also enhance investor visibility and possibly help stabilize the stock price.

Considering these risks, investors might explore diversification strategies like the Trefis Reinforced Value (RV) Portfolio, which has outperformed its all-cap stocks benchmark (a combination of the S&P 500, S&P mid-cap, and Russell 2000 benchmark indices) to deliver strong returns to investors. The quarterly rebalanced mix of large-, mid-, and small-cap RV Portfolio stocks offers a dynamic way to capitalize on favorable market conditions while mitigating losses when markets decline, as outlined in RV Portfolio performance metrics.

Here are five stocks added to the Zacks Rank #1 (Strong Buy) List today:

Newmont Corporation (NEM - Free Report) : This producer and explorer of gold and other metals has seen the Zacks Consensus Estimate for its current year earnings increasing 6.9% over the last 60 days.

Royal Bank of Canada (RY - Free Report) : This diversified financial services company has seen the Zacks Consensus Estimate for its current year earnings increasing 5.6% over the last 60 days.

Amer Sports, Inc. (AS - Free Report) : This sports and outdoor brands company has seen the Zacks Consensus Estimate for its current year earnings increasing 9.1% over the last 60 days.

Verastem, Inc. (VSTM - Free Report) : This biopharmaceutical company has seen the Zacks Consensus Estimate for its current year earnings increasing 21.5% over the last 60 days.

Sono-Tek Corporation (SOTK - Free Report) : This precision ultrasonic coating systems company has seen the Zacks Consensus Estimate for its current year earnings increasing 37.5% over the last 60 days.

You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.

HomeInvestingCommoditiesOutside the BoxOutside the BoxIf China’s demand slows, gold’s price will decline. Much is riding on U.S.-China politics.Published: Oct. 21, 2025 at 7:45 a.m. ET

If someone told you in January to put $10,000 into gold GC00 instead of the Nasdaq Composite COMP or a bitcoin BTCUSD exchange-traded fund and that you’d thank them by October, you might not have believed it.

But gold has outshone them all; it is outperforming every major stock index from Shanghai to New York. The precious metal currently is at an all-time high and approaching $4,400 an ounce — yet there’s no global recession that typically would cause a flight to the safety of gold. On Oct. 15, JP Morgan Chase JPM Chief Executive Jamie Dimon said during a Fortune magazine event that “gold could easily to go $5,000 or $10,000 in environments like this.”

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Registration Link Below for October 28, 2025 12 PM EST Presentation and Live Q&A
October 21, 2025 7:45 AM EDT | Source: Phio Pharmaceuticals Corp.
King of Prussia, Pennsylvania--(Newsfile Corp. - October 21, 2025) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio announced today that Mr. Robert Bitterman, CEO and Chairman of the Board, Phio Pharmaceuticals will present an update on the company's proprietary INTASYL siRNA technology and progress on the on-going clinical trial with lead compound PH-762 for treatment of skin cancers. Recently, positive interim safety and efficacy results were reported in the on-going Phase 1b dose escalation clinical trial with the INTASYL compound PH-762 for the treatment of skin cancer.

Phio's presentation and live Q&A will take place on Tuesday, October 28, 2025, at 12:00 PM EST in the live Virtual Non-Deal Roadshow Series hosted by Renmark Financial Communications Inc. A replay of the event may be accessed on the Renmark Financial Communications Inc. website at https://www.renmarkfinancial.com/vndrs.

"All stakeholders, investors, and other individual followers are invited to join this event to learn more about Phio Pharmaceuticals and our continuing pursuit of innovative pathways towards a cancer free future using our INTASYL technology," stated Robert Bitterman, CEO and Chairman of Phio Pharmaceuticals.

REGISTER HERE: https://www.renmarkfinancial.com/live-registration/renmark-virtual-non-deal-roadshow-nasdaq-phio-m4qNBCVz4M

Please Note: If the link does not work, please copy and paste into your browser. To ensure smooth connectivity, please access the link above using the latest version of Google Chrome.

About Phio Pharmaceuticals Corp.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company advancing its INTASYL® gene silencing technology focused on immuno-oncology therapeutics. Phio's INTASYL compounds are designed to enhance the body's immune cells to more effectively kill cancer cells. Phio's lead clinical program is an INTASYL compound, PH-762, that silences the PD-1 gene implicated in various forms of skin cancer. The on-going Phase 1b trial (NCT# 06014086) is evaluating PH-762 for the treatment of cutaneous squamous cell carcinoma, melanoma and Merkel cell carcinoma. PH-762 is a potential non-surgical treatment for skin cancers.

For additional information, visit the Company's website, www.phiopharma.com.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements can be identified by words such as "intends," "believes," "anticipates," "indicates," "plans," "expects," "suggests," "may," "would," "should," "potential," "designed to," "will," "ongoing," "estimate," "forecast," "target," "predict," "could" and similar references, although not all forward-looking statements contain these words. Examples of forward-looking statements contained in this press release include, among others, the possibility that our INTASYL® siRNA gene silencing technology will make the body's immune cells more effective in killing cancer cells, the potential for additional potential applications across the INTASYL portfolio, expectations regarding timing of enrollment, and statements regarding our commercial and clinical strategy, development plans and timelines and other future events.  

These statements are based only on our current beliefs, expectations and assumptions and are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control.  Our actual results may differ materially from those indicated in the forward-looking statements as a result of a number of important factors, including, but not limited to, the impact to our business and operations by inflationary pressures, rising interest rates, recession fears, the development of our product candidates, results from our preclinical and clinical activities, our ability to execute on business strategies, our ability to develop our product candidates with collaboration partners, and the success of any such collaborations, the timeline and duration for advancing our product candidates into clinical development, the timing or likelihood of regulatory filings and approvals, the success of our efforts to commercialize our product candidates if approved, our ability to manufacture and supply our product candidates for clinical activities, and for commercial use if approved, the scope of protection we are able to establish and maintain for intellectual property rights covering our technology platform, our ability to obtain future financing, market and other conditions and those identified in our Annual Report on Form 10-K and subsequent Quarterly Reports on Form 10-Q under the caption "Risk Factors" and in other filings the Company periodically makes with the SEC. Readers are urged to review these risk factors and to not act in reliance on any forward-looking statements, as actual results may differ from those contemplated by our forward-looking statements. Phio does not undertake to update forward-looking statements to reflect a change in its views, events or circumstances that occur after the date of this release, except as required by law.  

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/270981

, /PRNewswire/ -- Peabody (NYSE: BTU) will discuss its third quarter 2025 financial results in an investor conference call on Thursday, Oct. 30, 2025, at 10:00 a.m. Central Time.

Interested participants may access the call using the following phone numbers:

U.S. Toll Free             1 833 816 1387
Canada Toll Free       1 855 669 9657
International Toll        1 412 317 0480

The call will also be webcast and accessible via the homepage at www.peabodyenergy.com or by clicking here. Following the live event, a replay will be available on the site.

Peabody's third quarter 2025 earnings release will be distributed via PR Newswire before the market opens on Oct. 30 and will be posted to the company's website at that time.

About Peabody: 
Peabody is a leading coal producer, providing essential products for the production of affordable, reliable energy and steel. Our commitment to sustainability underpins everything we do and shapes our strategy for the future. For further information, visit PeabodyEnergy.com.

Contact:
Vic Svec / Kala Finklang
[email protected]

SOURCE Peabody

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